MicroRNA genes are transcribed by RNA polymerase II
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Summary
The first direct evidence that miRNA genes are transcribed by RNA polymerase II (pol II) is presented and the detailed structure of a miRNA gene is described, for the first time, by determining the promoter and the terminator of mir‐23a∼27a‐24‐2.
- Type
- article
- Published
- 2004-10-13
- Cited by
- 4,603
- References
- 34
- Access
- Open access
- OpenAlex
- https://openalex.org/W15372072
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2007180
Keywords
Modified atmosphere, Atmosphere (unit), Index (typography), Respiration, Environmental science
References
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- Research Communication
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- bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila.
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- MicroRNAs Modulate Hematopoietic Lineage Differentiation
- Functional siRNAs and miRNAs exhibit strand bias.
- Identification of Virus-Encoded MicroRNAs
- miRNAs on the move: miRNA biogenesis and the RNAi machinery.
- MicroRNA precursors in motion: exportin-5 mediates their nuclear export.
- Exchange of N-CoR corepressor and Tip60 coactivator complexes links gene expression by NF-kappaB and beta-amyloid precursor protein.
Cited by
- A Biochemical Dissection of the RNA Interference Pathway in Drosophila melanogaster : A Dissertation
- Knock-down of gene expression in hematopoietic cells.
- Expression of Micro RNA192 in Type 2 Diabetes Mellitus Relation to Glycemic Control, Metabolic Abnormalities, Renal and Ocular Complications
- RARs and microRNAs.
- Transgenic animal models in biomedical research.
- Gene expression regulators —MicroRNAs
- Toward Personalized Medicine: The potential role of RNA interference in Plasma Cell Dyscrasia
- RNAi and Cellular miRNAs in Infections by Mammalian Viruses
- Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes.
- Role of Micro-RNAs in Regulation of Lentiviral Latency and Persistence
- In vitro precursor microRNA processing assays using Drosophila Schneider-2 cell lysates.
- Exploiting Drosophila genetics to understand microRNA function and regulation
- Therapeutic RNA interference for neurodegenerative diseases: From promise to progress.
- Translational Medicine: microRNAs: a new emerging class of players for disease diagnostics and gene therapy
- Genomic Organization of Zebrafish microRNAs
- Human cytomegalovirus microRNAs.
- miRNA expression profiling in melanocytes and melanoma cell lines reveals miRNAs associated with formation and progression of malignant melanoma.
- C19MC microRNAs are processed from introns of large Pol-II, non-protein-coding transcripts
- Identification of Nutrient-Responsive Arabidopsis and Rapeseed MicroRNAs by Comprehensive Real-Time Polymerase Chain Reaction Profiling and Small RNA Sequencing1[C][W][OA]
- Current knowledge of MicroRNAs and noncoding RNAs in virus-infected cells.
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