Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals
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Summary
It is demonstrated that specific lincRNAs are transcriptionally regulated by key transcription factors in these processes such as p53, NFκB, Sox2, Oct4 (also known as Pou5f1) and Nanog, defining a unique collection of functional linc RNAs that are highly conserved and implicated in diverse biological processes.
- Type
- article
- Published
- 2009-02-01
- Cited by
- 4,144
- References
- 45
- Access
- Open access
- OpenAlex
- https://openalex.org/W1999746344
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:653114
Keywords
Biology, Chromatin, Computational biology, Intergenic region, Genetics
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Cited by
- Detecting DNA-protein interactions in living cells--ChIP approach.
- PhyloCSF: a comparative genomics method to distinguish protein coding and non-coding regions
- Discovery and Annotation of Functional Chromatin Signatures in the Human Genome
- Transcriptional regulation of cellular senescence
- Noncoding RNAs in chromatin organization and transcription regulation: an epigenetic view.
- Methods for the Study of Long Noncoding RNA in Cancer Cell Signaling
- Effects of genome-wide copy number variation on expression in mammalian cells
- Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis.
- Human long non‐coding RNAs promote pluripotency and neuronal differentiation by association with chromatin modifiers and transcription factors
- Whole Transcriptome RNA-Seq Analysis of Breast Cancer Recurrence Risk Using Formalin-Fixed Paraffin-Embedded Tumor Tissue
- MicroRNAs and the Warburg Effect: new players in an old arena.
- A high throughput Chromatin ImmunoPrecipitation approach reveals principles of dynamic gene regulation in mammals
- The transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinoma.
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- Epigenetics in Sports
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- Discovering and mapping chromatin states using a tree hidden Markov model
- Potential Pathological and Functional Links Between Long Noncoding RNAs and Hematopoiesis
- The expression analysis of silk gland‐enriched intermediate‐size non‐coding RNAs in silkworm Bombyx mori
- Distinct Patterns of Genetic Variations in Potential Functional Elements in Long Noncoding RNAs
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