Polycomb proteins targeted by a short repeat RNA to the mouse X-chromosome
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Summary
It is concluded that a ncRNA cofactor recruits Polycomb complexes to their target locus and RepA, together with PRC2, is required for the initiation and spread of XCI.
- Type
- article
- Published
- 2008-10-31
- Cited by
- 1,639
- References
- 20
- Access
- Open access
- OpenAlex
- https://openalex.org/W1977943782
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6956285
Keywords
XIST, X-inactivation, PRC2, Biology, RNA
References
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- XIST RNA paints the inactive X chromosome at interphase: evidence for a novel RNA involved in nuclear/chromosome structure
- The Polycomb Group Protein EED Is Dispensable for the Initiation of Random X-Chromosome Inactivation
- Chromosomal silencing and localization are mediated by different domains of Xist RNA
- Perinucleolar targeting of the inactive X during S phase: evidence for a role in the maintenance of silencing.
- Role of Histone H3 Lysine 27 Methylation in X Inactivation
- Regulation of imprinted X-chromosome inactivation in mice by Tsix.
- Establishment of histone h3 methylation on the inactive X chromosome requires transient recruitment of Eed-Enx1 polycomb group complexes.
- Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAs.
- Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins.
- Recruitment of PRC1 function at the initiation of X inactivation independent of PRC2 and silencing
- Targeted mutagenesis of Tsix leads to nonrandom X inactivation.
- Evolutionary conservation of possible functional domains of the human and murine XIST genes.
Cited by
- Regulation of Adipocyte Transcription by PPARgamma Ligands
- The role of nuclear position and locus conformation in regulating V(D)J recombination of the Tcrb locus
- Mechanisms of Polycomb gene silencing: knowns and unknowns
- Intergenic transcription by RNA polymerase II coordinates Pol IV and Pol V in siRNA-directed transcriptional gene silencing in Arabidopsis.
- Noncoding RNAs in chromatin organization and transcription regulation: an epigenetic view.
- Methods for the Study of Long Noncoding RNA in Cancer Cell Signaling
- Systematic identification of long noncoding RNAs expressed during zebrafish embryogenesis.
- Hepatitis B virus X protein (HBx)‐related long noncoding RNA (lncRNA) down‐regulated expression by HBx (Dreh) inhibits hepatocellular carcinoma metastasis by targeting the intermediate filament protein vimentin
- The expression analysis of silk gland‐enriched intermediate‐size non‐coding RNAs in silkworm Bombyx mori
- The dynamics of X‐chromosome inactivation in mouse development
- Non-coding RNAs and the borders of heterochromatin
- Environmental Epigenetics: Crossroad between Public Health, Lifestyle, and Cancer Prevention
- Pervasive lncRNA binding by epigenetic modifying complexes--The challenges ahead.
- Unusual maintenance of X chromosome inactivation predisposes female lymphocytes for increased expression from the inactive X
- Altered Long Noncoding RNA Expression Precedes the Course of Parkinson’s Disease—a Preliminary Report
- Functions of long noncoding RNAs in the nucleus
- lncRNA MALAT1 binds chromatin remodeling subunit BRG1 to epigenetically promote inflammation-related hepatocellular carcinoma progression
- Etude du réseau transcriptionnel du gène Xist, acteur principal de l'inactivation du chromosome X
- Transcriptional gene silencing mediated by non-coding RNAs
- Regulation of the Kcnq1ot1 Imprinting Domain in Mouse
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