Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

Daniel J. Ceradini, Anita R. Kulkarni, Matthew J. Callaghan, Oren M. Tepper, Nicholas Bastidas · Nature Medicine · 2004

Summary

It is shown that SDF-1 gene expression is regulated by the transcription factor hypoxia-inducible factor-1 (HIF-1) in endothelial cells, resulting in selective in vivo expression of S DF-1 in ischemic tissue in direct proportion to reduced oxygen tension.

Type: article
Published: 2004-08-01
Cited by: 2,766
References: 30
DOI: https://doi.org/10.1038/nm1075
PubMed: https://pubmed.ncbi.nlm.nih.gov/15235597/
OpenAlex: https://openalex.org/W1982861439
Semantic Scholar: https://api.semanticscholar.org/CorpusID:10524639

Keywords

Progenitor cell, Cell biology, Homing (biology), Stromal cell, Stromal cell-derived factor 1

References

Ischemia- and cytokine-induced mobilization of bone marrow-derived endothelial progenitor cells for neovascularizationTomono Takahashi, Christoph Kalka, Haruchika Masuda — 1999
Chemokines and the arrest of lymphocytes rolling under flow conditions.James J. Campbell, Joseph A. Hedrick, Albert Zlotnik — 1998
Therapeutic Potential of Ex Vivo Expanded Endothelial Progenitor Cells for Myocardial IschemiaAtsuhiko Kawamoto, Heon-Cheol Gwon, Hideki Iwaguro — 2001
Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4.Kathleen E. McGrath, Anne D. Koniski, Kathleen M. Maltby — 1999
Chemokine receptor CXCR4 downregulated by von Hippel–Lindau tumour suppressor pVHLPeter Staller, Jitka Sulitkova, Joanna Lisztwan — 2003
Targeting HIF-1 for cancer therapyGregg L. Semenza — 2003
Stromal cell-derived factor 1 is secreted by meningeal cells and acts as chemotactic factor on neuronal stem cells of the cerebellar external granular layer.K Reiss, Rolf Mentlein, Jobst Sievers — 2002
Age-dependent Defect in Vascular Endothelial Growth Factor Expression Is Associated with Reduced Hypoxia-inducible Factor 1 Activity*Alain Rivard, Laurence Berthou-Soulié, Nicole Principe — 2000
Isolation of Putative Progenitor Endothelial Cells for AngiogenesisTakayuki Asahara, Toyoaki Murohara, Alison Sullivan — 1997
Hypoxia-induced production of stromal cell-derived factor 1 (CXCL12) and vascular endothelial growth factor by synovial fibroblasts.Carol Hitchon, Keng Wong, Guoping Ma — 2002
Expression of Functional CXCR4 by Muscle Satellite Cells and Secretion of SDF‐1 by Muscle‐Derived Fibroblasts is Associated with the Presence of Both Muscle Progenitors in Bone Marrow and Hematopoietic Stem/Progenitor Cells in MusclesMariusz Z. Ratajczak, Marcin Majka, Magda Kucia — 2003
Oxygen saturation in the bone marrow of healthy volunteers.Jonathan S. Harrison, Pranela Rameshwar, Victor T. Chang — 2002
Regulation of hypoxia-inducible factor 1α is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathwayEric Huang, Jie Gu, Maureen Schau — 1998
Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1Takashi Nagasawa, Seiichi Hirota, Kazunobu Tachibana — 1996
Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar developmentYong-Rui Zou, Andreas H. Kottmann, Masahiko Kuroda — 1998
Sulfated polysaccharides increase plasma levels of SDF-1 in monkeys and mice: involvement in mobilization of stem/progenitor cells.Elizabeth Sweeney, Hugues Lortat‐Jacob, Gregory V. Priestley — 2002
Human Endothelial Progenitor Cells From Type II Diabetics Exhibit Impaired Proliferation, Adhesion, and Incorporation Into Vascular StructuresOren M. Tepper, Robert D. Galiano, Jennifer M. Capla — 2002
HMG-CoA reductase inhibitors (statins) increase endothelial progenitor cells via the PI 3-kinase/Akt pathway.Stefanie Dimmeler, Alexandra Aicher, Mariuca Vasa — 2001
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liver.Órit Kollet, Shoham Shivtiel, Yuan-Qing Chen — 2003
Stromal Cell–Derived Factor-1 Effects on Ex Vivo Expanded Endothelial Progenitor Cell Recruitment for Ischemic NeovascularizationJun‐ichi Yamaguchi, Kengo Kusano, Osamu Masuo — 2003

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Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1

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