G-protein-coupled receptors and cancer
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Summary
This Review will address the current understanding of the many roles of GPCRs and their signalling circuitry in tumour progression and metastasis and discuss how interfering with GPCR might provide unique opportunities for cancer prevention and treatment.
- Type
- article
- Published
- 2007-02-01
- Cited by
- 1,428
- References
- 160
- OpenAlex
- https://openalex.org/W17251915
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10996598
Keywords
Computer science
References
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- G Protein β3 subunit gene C825T polymorphism and its association with the presence and clinicopathological characteristics of prostate cancer.
- Pristimerin inhibits breast cancer cell migration by up- regulating regulator of G protein signaling 4 expression.
- PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells
- GNG2 inhibits invasion of human malignant melanoma cells with decreased FAK activity.
- EGFR‐mediated Akt and MAPKs signal pathways play a crucial role in patulin‐induced cell proliferation in primary murine keratinocytes via modulation of Cyclin D1 and COX‐2 expression
- Cyclic AMP (cAMP) signaling in melanocytes and melanoma.
- RGS16, a novel p53 and pRb cross-talk candidate inhibits migration and invasion of pancreatic cancer cells
- Expression of Beclin Family Proteins Is Associated with Tumor Progression in Oral Cancer
- Making Sense of Pharmacology: Inverse Agonism and Functional Selectivity
- Contributions of Academic Labs to the Discovery and Development of Chemical Biology Tools
- Therapeutic targets in neuroendocrine tumours
- Study of the Structure and Function of CXC Chemokine Receptor 2
- Wege zur personalisierten Medizin beim Magenkarzinom
- The Role of Chemokine Receptor CXCR7 with EGFR in Breast Cancer Cell Proliferation
- BDNF/TrkB em câncer colorretal : interações funcionais com GRPR e EGFR
- Receptor do peptídeo liberador de gastrina (GRPR) em gliomas : expressão, influência na proliferação celular e mecanismos de sinalização
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