Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus
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Summary
A common receptor activation pathway can initiate innate immune responses to both bacterial and viral pathogens.
- Type
- article
- Published
- 2000-11-01
- Cited by
- 1,830
- References
- 41
- Access
- Open access
- OpenAlex
- https://openalex.org/W1499978168
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:40280008
Keywords
Pattern recognition receptor, Innate immune system, Biology, CD14, Receptor
References
- CD40 Ligand (CD154) Enhances the Th1 and Antibody Responses to Respiratory Syncytial Virus in the BALB/c Mouse
- Recognition of bacterial endotoxins by receptor-dependent mechanisms.
- Cloning and characterization of two Toll/Interleukin-1 receptor-like genes TIL3 and TIL4: evidence for a multi-gene receptor family in humans.
- A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
- Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus.
- Toll-like receptor-2 mediates lipopolysaccharide-induced cellular signalling
- Mycobacterial lipoarabinomannan recognition requires a receptor that shares components of the endotoxin signaling system.
- Enhancement of respiratory syncytial virus pulmonary pathology in cotton rats by prior intramuscular inoculation of formalin-inactiva ted virus
- Antimicrobial peptide defense in Drosophila
- Peptidoglycan- and Lipoteichoic Acid-induced Cell Activation Is Mediated by Toll-like Receptor 2*
- CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein.
- Polymyxin-B inhibition of LPS-induced interleukin-1 secretion by human monocytes is dependent upon the LPS origin.
- From the National Institute of Allergy and Infectious Diseases and the World Health Organization. Respiratory syncytial and parainfluenza viruses.
- Cell activation and apoptosis by bacterial lipoproteins through toll-like receptor-2.
- Toll-like Receptor-4 Mediates Lipopolysaccharide-induced Signal Transduction*
- Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components.
- CD14 is a pattern recognition receptor.
- The 18‐wheeler mutation reveals complex antibacterial gene regulation in Drosophila host defense
- Heterotrimeric G proteins physically associated with the lipopolysaccharide receptor CD14 modulate both in vivo and in vitro responses to lipopolysaccharide.
- MD-2, a Molecule that Confers Lipopolysaccharide Responsiveness on Toll-like Receptor 4
Cited by
- Paramyxoviruses crossing the host membrane: mechanisms for entry
- The interactions of Kaposi's sarcoma-associated herpesvirus with human toll-like receptors and human papillomavirus and pdz-domain containing proteins
- Cinderella goes to the ball
- The interferon antiviral response: from viral invasion to evasion
- Lipopolysaccharide Stimulates p38-dependent Induction of Antiviral Genes in Neutrophils Independently of Paracrine Factors*
- Toll-like receptor signaling in sepsis
- Infectious triggers of pediatric asthma.
- Injury, sepsis, and the regulation of Toll‐like receptor responses
- Viral respiratory infection and the link to asthma
- The role of Toll‐like receptor 4 versus interleukin‐12 in immunity to respiratory syncytial virus
- Innate immunity against vaccinia virus is mediated by TLR2 and requires TLR-independent production of IFN-beta.
- Viral and Host Factors in Human Respiratory Syncytial Virus Pathogenesis
- TLR accessory molecules.
- Viral evasion and subversion of pattern-recognition receptor signalling
- Human cytomegalovirus interacts with toll-like receptor 2 and CD14 on syncytiotrophoblasts to stimulate expression of TNFalpha mRNA and apoptosis.
- Respiratory Viral Infections in Infants: Causes, Clinical Symptoms, Virology, and Immunology
- Pattern Recognition via the Toll-Like Receptor System in the Human Female Genital Tract
- Dendritic cells and measles virus infection.
- Transforming Growth Factor Beta Is a Major Regulator of Human Neonatal Immune Responses following Respiratory Syncytial Virus Infection
- Local cytokine response upon respiratory syncytial virus infection.
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