Families of retinoid dehydrogenases regulating vitamin A function: production of visual pigment and retinoic acid.

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Summary

Compilation of the known retinoid dehydrogenases indicates the existence of 17 nonorthologous forms: five ADHs, eight SDRs, and four ALDHs,Eight of which are conserved in both mouse and human, suggesting a function in androgen metabolism as well as retinoids metabolism.

Type
review
Published
2000-07-01
Cited by
625
References
118

Keywords

Retinoid, Aldehyde dehydrogenase, Retinoid X receptor beta, Retinoic acid, Retinoid X receptor alpha

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