Epithelial-to-mesenchymal transition: what is the impact on breast cancer stem cells and drug resistance.
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Summary
Definition of the exact molecular mechanisms that are involved in the generation of stem cells through EMT could lead to the identification of new potential therapeutic targets and enable the development of more efficient strategies for particular patient groups.
- Type
- article
- Published
- 2014-04-01
- Cited by
- 232
- References
- 251
- Access
- Open access
- OpenAlex
- https://openalex.org/W24090504
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12516138
Keywords
Storytelling, Ran, Psychology, Sleep (system call), Developmental psychology
References
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- Mesenchymal to Epithelial Transition in Development and Disease
Cited by
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- Implications of Akt2/Twist crosstalk on breast cancer metastatic outcome.
- EpCAM-Antibody-Labeled Noncytotoxic Polymer Vesicles for Cancer Stem Cells-Targeted Delivery of Anticancer Drug and siRNA.
- Translational Horizons in the Tumor Microenvironment: Harnessing Breakthroughs and Targeting Cures
- Acquisition of resistance to trastuzumab in gastric cancer cells is associated with activation of IL-6/STAT3/Jagged-1/Notch positive feedback loop
- Quercetin regulates β‐catenin signaling and reduces the migration of triple negative breast cancer
- Elevated STAT3 Signaling-Mediated Upregulation of MMP-2/9 Confers Enhanced Invasion Ability in Multidrug-Resistant Breast Cancer Cells
- The network of pluripotency, epithelial–mesenchymal transition, and prognosis of breast cancer
- Epithelial-mesenchymal transition and drug resistance in breast cancer (Review).
- Differential expression of epithelial–mesenchymal transition and stem cell markers in intrinsic subtypes of breast cancer
- Glial Progenitors as Targets for Transformation in Glioma
- 53BP1 suppresses epithelial–mesenchymal transition by downregulating ZEB1 through microRNA-200b/429 in breast cancer
- The Multifaceted Mechanism of Leptin Signaling within Tumor Microenvironment in Driving Breast Cancer Growth and Progression
- Seeing through the trick of cancer cells via 2D gels
- Acquisition of epithelial–mesenchymal transition is associated with Skp2 expression in paclitaxel-resistant breast cancer cells
- An IL6-STAT3 loop mediates resistance to PI3K inhibitors by inducing epithelial-mesenchymal transition and cancer stem cell expansion in human breast cancer cells.
- Down-regulation of Gli-1 inhibits hepatocellular carcinoma cell migration and invasion
- The impact of tumor stroma on drug response in breast cancer.
- Deconstructing breast cancer cell biology and the mechanisms of multidrug resistance.
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