Discover the network mechanisms underlying the connections between aging and age-related diseases
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Summary
It is shown that aging has stronger connections with ARD genes compared to non-ARD genes in subnetworks corresponding to various biological processes, and GeroNet identifies meaningful genes that may play key roles in connecting aging and ARDs.
- Type
- article
- Published
- 2016-09-01
- Cited by
- 38
- References
- 68
- Access
- Open access
- OpenAlex
- https://openalex.org/W27582315
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:17834019
Keywords
Philosophy
References
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Cited by
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- A novel approach of human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases
- Cross talk of chromosome instability, CpG island methylator phenotype and mismatch repair in colorectal cancer
- Integrative Approach to Sporadic Alzheimer’s Disease: Deficiency of driver Tyrobp/Dap12 in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden
- An Efficient Classifier for Alzheimer’s Disease Genes Identification
- Roles of Phenolic Compounds in the Reduction of Risk Factors of Cardiovascular Diseases
- Exercise-induced AMPK activation is involved in delay of skeletal muscle senescence.
- Exploiting Discriminative Regions of Brain Slices Based on 2D CNNs for Alzheimer’s Disease Classification
- A Random Forest Sub-Golgi Protein Classifier Optimized via Dipeptide and Amino Acid Composition Features
- Human geroprotector discovery by targeting the converging subnetworks of aging and age-related diseases
- DNA methylation profile is a quantitative measure of biological aging in children
- Exploration of the correlation between GPCRs and drugs based on a learning to rank algorithm
- Revealing the Interactions Between Diabetes, Diabetes-Related Diseases, and Cancers Based on the Network Connectivity of Their Related Genes
- Proteodynamics and aging of eukaryotic cells.
- Biological mechanisms of aging predict age-related disease multimorbidities in patients
- Identifying Breast Cancer-Related Genes Based on a Novel Computational Framework Involving KEGG Pathways and PPI Network Modularity
- A Computational Framework to Identify Transcriptional and Network Differences between Hepatocellular Carcinoma and Normal Liver Tissue and Their Applications in Repositioning Drugs
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