The impact of reactive oxygen species and genetic mitochondrial mutations in Parkinson's disease.
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Summary
This paper expands on the specific impact of mitochondrial genetic change and production of free radicals as well as its correlation to the neurodegeneration in Parkinson's disease.
- Type
- review
- Published
- 2013-12-10
- Cited by
- 194
- References
- 110
- OpenAlex
- https://openalex.org/W2032730372
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205017517
Keywords
Biology, Neurodegeneration, Reactive oxygen species, Parkinson's disease, PINK1
References
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- Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
- Mechanism of Toxicity in Rotenone Models of Parkinson's Disease
- Catecholamine content and in vitro catecholamine synthesis in peripheral human lymphocytes.
- Phase analysis identifies compound heterozygous deletions of the PARK2 gene in patients with early‐onset Parkinson disease
- DJ-1 regulation of mitochondrial function and autophagy through oxidative stress
- Prevalence of Parkinson's disease in the elderly
- Reduced dopamine in peripheral blood lymphocytes in Parkinson's disease.
- Formation, Prevention, and Repair of DNA Damage by Iron/Hydrogen Peroxide*
- Reactive oxygen species: from health to disease.
- Glutathione: an overview of biosynthesis and modulation.
- Astrocytes and Brain Injury
Cited by
- Nanomedicine-Based Neuroprotective Strategies in Patient Specific-iPSC and Personalized Medicine
- Discover the network mechanisms underlying the connections between aging and age-related diseases
- Neuroprotective effect of combined therapy with hyperbaric oxygen and madopar on 6-hydroxydopamine-induced Parkinson's disease in rats.
- Peganum Harmala L. Extract Reduces Oxidative Stress and Improves Symptoms in 6-Hydroxydopamine-Induced Parkinson’s Disease in Rats
- Oxidative Modulation of K+ Channels in the Central Nervous System in Neurodegenerative Diseases and Aging
- Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells
- Resveratrol relieves ischemia-induced oxidative stress in the hippocampus by activating SIRT1.
- Metabolite and Peptide Levels in Plasma and CSF Differentiating Healthy Controls from Patients with Newly Diagnosed Parkinson's Disease
- β‐elemene reverses the drug resistance of A549/DDP lung cancer cells by activating intracellular redox system, decreasing mitochondrial membrane potential and P‐glycoprotein expression, and inducing apoptosis
- Oxidative stress and Parkinson’s disease
- The roles of redox enzymes in Parkinson’s disease: Focus on glutaredoxin
- Age-dependent action of reactive oxygen species on transmitter release in mammalian neuromuscular junctions.
- Biological and physiological role of reactive oxygen species – the good, the bad and the ugly
- Estrogen receptor variant ER-α36 is involved in estrogen neuroprotection against oxidative toxicity.
- Protective effects of isolecanoric acid on neurodegenerative in vitro models.
- In Vitro/In Vivo Toxicity Evaluation and Quantification of Iron Oxide Nanoparticles
- Pterostilbene mediates neuroprotection against oxidative toxicity via oestrogen receptor α signalling pathways
- Spreading of pathology in neurodegenerative diseases: a focus on human studies
- The emergence of the mitochondrial genome as a partial regulator of nuclear function is providing new insights into the genetic mechanisms underlying age-related complex disease
- Alimentation, pesticides et pathologies neurologiques
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