Restoration of adiponectin expression via the ERK pathway in TNFα-treated 3T3-L1 adipocytes.
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Summary
The inhibitory effects of TNF‑α on adiponectin levels in differentiated 3T3‑L1 cells were fully reversed following a wash‑out period equivalent to the TNF‐α treatment time, potentially through the ERK 1/2 pathway.
- Type
- dissertation
- Published
- 2014-08-01
- Cited by
- 21
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W24890319
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22736860
Keywords
Political science, Humanities, Philosophy
References
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- c-Jun N-terminal kinase is involved in the suppression of adiponectin expression by TNF-alpha in 3T3-L1 adipocytes.
- Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ
- Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.
- Negative regulation of peroxisome proliferator-activated receptor-gamma gene expression contributes to the antiadipogenic effects of tumor necrosis factor-alpha.
- Visceral Fat Adipokine Secretion Is Associated With Systemic Inflammation in Obese Humans
- Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys.
Cited by
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- Variation in x-box binding protein 1 (XBP1) expression and its dependent endoplasmic reticulum chaperones does not regulate adiponectin secretion in dairy cows.
- Alogliptin improves endothelial function by promoting autophagy in perivascular adipose tissue of obese mice through a GLP-1-dependent mechanism.
- PPARβ/δ agonist GW501516 inhibits TNFα-induced repression of adiponectin and insulin receptor in 3T3-L1 adipocytes.
- Weight Gain, Conditioning and Metabolic Syndrome: A Sled Dog Model
- Myeloma Cells Down‐Regulate Adiponectin in Bone Marrow Adipocytes Via TNF‐Alpha
- Soy Isoflavone Genistein Is a Potential Agent for Metabolic Syndrome Treatment: A Narrative Review
- Senescence and adiponectin signaling - Studies in canine testis.
- Emerging Protein Biomarkers for the Diagnosis or Prediction of Gestational Diabetes—A Scoping Review
- Insulin increases adipose adiponectin in pregnancy by inhibiting ubiquitination and degradation: Impact of obesity.
- Upregulation of adiponectin by Ginsenoside Rb1 contributes to amelioration of hepatic steatosis induced by high fat diet
- A Potential Interplay between HDLs and Adiponectin in Promoting Endothelial Dysfunction in Obesity
- Modulation of adipose inflammation by cellular retinoic acid-binding protein 1
- Obesity: a perfect storm for carcinogenesis
- Effect of Exercise and Detraining on Signs of Puberty and Selected Inflammatory Markers in Girls with Precocious Puberty
- Main Colonic Metabolites from Coffee Chlorogenic Acid May Counteract Tumor Necrosis Factor-α-Induced Inflammation and Oxidative Stress in 3T3-L1 Cells
- Novel perspectives on the link between obesity and cancer risk: from mechanisms to clinical implications
- Hypoglycemia and hyperinsulinemia induced by phenolic uremic toxins in CKD and DKD patients
- Cardiometabolic Markers in Algerian Obese Subjects with and Without Type 2 Diabetes: Adipocytokine Imbalance as a Risk Factor
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