SOX2 Expression and Prognostic Significance in Ovarian Carcinoma
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Summary
This study correlates SOX2 protein expression and gene-amplification status in ovarian carcinomas with histopathologic criteria and disease outcome, and investigates whether expression of SoX2 has a specific role in prognosis and therapy response.
- Type
- article
- Published
- 2013-07-01
- Cited by
- 43
- References
- 43
- OpenAlex
- https://openalex.org/W23722508
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26415672
Keywords
Polydimethylsiloxane, Electroluminescence, Materials science, Polymer, Electrode
References
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- SOX2 amplification is a common event in squamous cell carcinomas of different organ sites.
- Shortened Telomeres in Serous Tubal Intraepithelial Carcinoma: An Early Event in Ovarian High-grade Serous Carcinogenesis
- Expression of the embryonic stem cell marker SOX2 in early-stage breast carcinoma
- Notch3 overexpression is related to the recurrence of ovarian cancer and confers resistance to carboplatin.
- Molecular Pathogenesis and Extraovarian Origin of Epithelial Ovarian Cancer. Shifting the Paradigm
- SOX2 PROTEIN EXPRESSION IS AN INDEPENDENT POOR PROGNOSTIC INDICATOR IN STAGE I LUNG ADENOCARCINOMA
- Role of Sox2 in the development of the mouse neocortex.
- Notch3 gene amplification in ovarian cancer.
- A Pathologist's Road Map to Benign, Precancerous, and Malignant Intraepithelial Proliferations in the Fallopian Tube
- Regulation of Self‐Renewal and Pluripotency by Sox2 in Human Embryonic Stem Cells
- Chromosomal losses of regions on 5q and lack of high‐level amplifications at 8q24 are associated with favorable prognosis for ovarian serous carcinoma
- Diagnosis of Ovarian Carcinoma Cell Type is Highly Reproducible: A Transcanadian Study
- SOX2 gene amplification and protein overexpression are associated with better outcome in squamous cell lung cancer
- CD133 expression associated with poor prognosis in ovarian cancer
- Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy
- Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival
- Molecular genetics for the clinician
- Expression of Sox2 in human ovarian epithelial carcinoma
- Expression of gastric mucin MUC5AC and gastric transcription factor SOX2 in ampulla of vater adenocarcinoma: comparison between expression patterns and histologic subtypes.
Cited by
- Screening the Molecular Targets of Ovarian Cancer Based on Bioinformatics Analysis
- Overexpression of Class III β-tubulin, Sox2, and nuclear Survivin is predictive of taxane resistance in patients with stage III ovarian epithelial cancer
- The overexpression of SOX2 affects the migration of human teratocarcinoma cell line NT2/D1.
- Aberrant SOX2 expression in colorectal cancers does not correlate with mucinous differentiation and gastric mucin MUC5AC expression
- High Expression of SOX2 Is Associated with Poor Prognosis in Patients with Salivary Gland Adenoid Cystic Carcinoma
- Evaluation of stem cell properties in human ovarian carcinoma cells using multi and single cell-based spheres assays.
- Low expression of mixed lineage kinase domain-like protein is associated with poor prognosis in ovarian cancer patients
- SOX2 expression associates with stem cell state in human ovarian carcinoma.
- Overexpression of TRPM7 is associated with poor prognosis in human ovarian carcinoma.
- SOX2 Expression Is Regulated by BRAF and Contributes to Poor Patient Prognosis in Colorectal Cancer
- Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma.
- Molecular and functional interactions between AKT and SOX2 in breast carcinoma
- HLA ligandomics identifies histone deacetylase 1 as target for ovarian cancer immunotherapy
- SOX2 expression is associated with a cancer stem cell state and down-regulation of CDX2 in colorectal cancer
- Stemness-Related Markers in Cancer
- The immunopeptidomic landscape of ovarian carcinomas
- Gynecologic Serous Carcinoma: An Immunohistochemical Analysis of Malignant Body Fluid Specimens.
- Dr. Jekyl-Mr. Hyde Role of Sox Family–From Neurogenesis to Cancer: A Review.
- SOX2 in cancer stemness: tumor malignancy and therapeutic potentials
- SOX2 protein biochemistry in stemness, reprogramming, and cancer: the PI3K/AKT/SOX2 axis and beyond
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