Optimization of the intravenous glucose tolerance test in T2DM patients using optimal experimental design
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Summary
It is concluded that improvement can be made to the design of the insulin modified IVGTT and that the most important design factor was the placement of sample times followed by the use of an optimal insulin dose.
- Type
- article
- Published
- 2009-06-25
- Cited by
- 21
- References
- 23
- OpenAlex
- https://openalex.org/W19554431
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:11446164
Keywords
Political science, Business
References
- An Integrated Model for Glucose and Insulin Regulation in Healthy Volunteers and Type 2 Diabetic Patients Following Intravenous Glucose Provocations
- Simultaneous optimal experimental design on dose and sample times
- Robust Optimal Design for the Estimation of Hyperparameters in Population Pharmacokinetics
- Modified protocols improve insulin sensitivity estimation using the minimal model.
- Robust Population Pharmacokinetic Experiment Design
- POPED, a software for optimal experiment design in population kinetics
- Pharmacokinetic/Pharmacodynamic Modelling in Diabetes Mellitus
- Pharmacodynamics of NN2211, a novel long acting GLP-1 derivative.
- A reduced sampling schedule for estimating the parameters of the glucose minimal model from a labeled IVGTT
- Robust experiment design via stochastic approximation
- Minimal model analysis of intravenous glucose tolerance test-derived insulin sensitivity in diabetic subjects.
- Intravenous Glucose Tolerance as a Tool in Definition and Diagnosis of Diabetes Mellitus*
- Development and implementation of the population Fisher information matrix for the evaluation of population pharmacokinetic designs
- Quantitative estimation of insulin sensitivity.
- Approaches to handling pharmacodynamic baseline responses
- The Insulin Sensitivity Index in Nondiabetic Man: Correlation Between Clamp-derived and IVGTT-derived Values
- Further Developments of the Fisher Information Matrix in Nonlinear Mixed Effects Models with Evaluation in Population Pharmacokinetics
- The iterative two-stage population approach to IVGTT minimal modeling: improved precision with reduced sampling. Intravenous glucose tolerance test.
- Bayesian Optimal Designs for Pharmacokinetic Models: Sensitivity to Uncertainty
- [Intravenous glucose tolerance test].
Cited by
- Characterization of frequently sampled intravenous glucose tolerance test using scaling and sensitivity analysis of MINMOD
- Modelling endocrine regulation of glycaemic control in animal models of diabetes
- Optimal sampling of antipsychotic medicines: a pharmacometric approach for clinical practice.
- Semimechanistic model describing gastric emptying and glucose absorption in healthy subjects and patients with type 2 diabetes
- Clinical Trial Simulation: A Review
- Population based optimal experimental design in cancer diagnosis and chemotherapy: In silico analysis
- Model‐based design of experiments for cellular processes
- An integrated model for the glucose-insulin system.
- D optimal designs for three Poisson dose–response models
- Model‐Based Interspecies Scaling of Glucose Homeostasis
- Reduced and optimized trial designs for drugs described by a target mediated drug disposition model
- Translation Between Two Models; Application with Integrated Glucose Homeostasis Models
- Model-Based Conditional Weighted Residuals Analysis for Structural Model Assessment
- Pharmacometric models in the development of biological medicinal products
- On Optimal Designs for Clinical Trials: An Updated Review
- Development of early diagnosis of Parkinson's disease: Illusion or reality?
- Optimal Designs for Model‐Based Assessment of Insulin Sensitivity and Glucose Effectiveness
- Accelerated Predictive Healthcare Analytics with Pumas, A High Performance Pharmaceutical Modeling and Simulation Platform
- A snapshot of the vast array of diamagnetic CEST MRI contrast agents
- Optimal Experimental Design to Estimate Insulin Response in Type 2 Diabetes
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