Intercellular Signaling Pathways Active During Intervertebral Disc Growth, Differentiation, and Aging
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Summary
A spatial/temporal map of the signaling pathways active in the postnatal intervertebral disc during growth, differentiation, and aging of the disc is presented.
- Type
- article
- Published
- 2009-03-01
- Cited by
- 63
- References
- 26
- Access
- Open access
- OpenAlex
- https://openalex.org/W19212276
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7012715
Keywords
Computer science
References
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Cited by
- Investigating the cell population of the adult human nucleus pulposus
- Diversity of intervertebral disc cells: phenotype and function
- Defining the Phenotype of Young Healthy Nucleus Pulposus Cells: Recommendations of the Spine Research Interest Group at the 2014 Annual ORS Meeting
- Intercellular Signaling Pathways Active During and After Growth and Differentiation of the Lumbar Vertebral Growth Plate
- Characterization of the human nucleus pulposus cell phenotype and evaluation of novel marker gene expression to define adult stem cell differentiation.
- Differentiation of Mouse Induced Pluripotent Stem Cells (iPSCs) into Nucleus Pulposus-Like Cells In Vitro
- Hedgehog signaling is required for formation of the notochord sheath and patterning of nuclei pulposi within the intervertebral discs
- Biochemical composition and turnover of the extracellular matrix of the normal and degenerate intervertebral disc
- Notochordal Cell-Derived Therapeutic Strategies for Discogenic Back Pain
- The aging mouse partially models the aging human spine: lumbar and coccygeal disc height, composition, mechanical properties, and Wnt signaling in young and old mice.
- Wnt Signaling Activates Shh Signaling in Early Postnatal Intervertebral Discs, and Re-Activates Shh Signaling in Old Discs in the Mouse
- Shh Signaling from the Nucleus Pulposus Is Required for the Postnatal Growth and Differentiation of the Mouse Intervertebral Disc
- Dynamic pressurization induces transition of notochordal cells to a mature phenotype while retaining production of important patterning ligands from development
- Inactivation of Patched1 in Murine Chondrocytes Causes Spinal Fusion Without Inflammation
- Degeneration and regeneration of the intervertebral disc: lessons from development
- TGF‐β1 and GDF5 Act Synergistically to Drive the Differentiation of Human Adipose Stromal Cells toward Nucleus Pulposus‐like Cells
- Notochord Morphogenesis in Mice: Current Understanding & Open Questions
- Oestrogen and parathyroid hormone alleviate lumbar intervertebral disc degeneration in ovariectomized rats and enhance Wnt/β-catenin pathway activity
- Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs
- A Controlled Release Codelivery System of MSCs Encapsulated in Dextran/Gelatin Hydrogel with TGF-β3-Loaded Nanoparticles for Nucleus Pulposus Regeneration
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