Differentiation of Mouse Induced Pluripotent Stem Cells (iPSCs) into Nucleus Pulposus-Like Cells In Vitro
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Summary
It is suggested that mouse iPSCs have the potential to differentiate into NP-like cells and suggests the possibility that they may be used as a novel cell source for cellular therapy in the IVD.
- Type
- article
- Published
- 2013-09-25
- Cited by
- 65
- References
- 74
- Access
- Open access
- OpenAlex
- https://openalex.org/W1998182018
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2134546
Keywords
Induced pluripotent stem cell, Cell biology, Population, Biology, Stem cell
References
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- Differentiation of Mesenchymal Stem Cells Towards a Nucleus Pulposus-like Phenotype In Vitro: Implications for Cell-Based Transplantation Therapy
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- Clinical experience in cell-based therapeutics: disc chondrocyte transplantation A treatment for degenerated or damaged intervertebral disc.
- Aging and degeneration of the human intervertebral disc.
- Diversity of intervertebral disc cells: phenotype and function
- 1991 Volvo Award in Basic Sciences: Collagen Types Around the Cells of the Intervertebral Disc and Cartilage End Plate: An Immunolocalization Study
- Expression of Laminin Isoforms, Receptors and Binding Proteins Unique to Nucleus Pulposus Cells of Immature Intervertebral Disc
- Ultrastructure of the human intervertebral disc. I. Changes in notochordal cells with age.
- Growth factors and the intervertebral disc.
- Matrix protein gene expression in intervertebral disc cells subjected to altered osmolarity.
- Postnatal Growth, Differentiation, and Aging of the Mouse Intervertebral Disc
- Cartilage tissue engineering using differentiated and purified induced pluripotent stem cells
- Generation of induced pluripotent stem cell lines from adult rat cells.
- Exhaustion of nucleus pulposus progenitor cells with ageing and degeneration of the intervertebral disc
- Derivation of induced pluripotent stem cells from pig somatic cells
- Intervertebral Disc Cell Therapy for Regeneration: Mesenchymal Stem Cell Implantation in Rat Intervertebral Discs
- Bunched, the Drosophila homolog of the mammalian tumor suppressor TSC-22, promotes cellular growth
- Percutaneous Reinsertion of the Nucleus Pulposus: An Experimental Study
Cited by
- Neuronal production from induced pluripotent stem cells in self-assembled collagen-hyaluronic acid-alginate microgel scaffolds with grafted GRGDSP/Ln5-P4.
- Defining the Phenotype of Young Healthy Nucleus Pulposus Cells: Recommendations of the Spine Research Interest Group at the 2014 Annual ORS Meeting
- [Regenerative medicine of the intervertebral disc: from pathophysiology to clinical application].
- Developments in intervertebral disc disease research: pathophysiology, mechanobiology, and therapeutics
- Intervertebral disc regeneration: a great challenge for tissue engineers.
- Stem Cell Therapy for Intervertebral Disk Regeneration
- Stem cell therapy for intervertebral disc regeneration: obstacles and solutions
- Modulating Notochordal Differentiation of Human Induced Pluripotent Stem Cells Using Natural Nucleus Pulposus Tissue Matrix
- Intact Glycosaminoglycans from intervertebral disc-derived notochordal cell conditioned media inhibits neurite growth while maintaining neuronal cell viability
- Inflammation in intervertebral disc degeneration and regeneration
- Novel immortal human cell lines reveal subpopulations in the nucleus pulposus
- Intervertebral Disc Engineering through Exploiting Mesenchymal Stem Cells: Progress and Perspective.
- Activation of intervertebral disc cells by co-culture with notochordal cells, conditioned medium and hypoxia
- Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord‐specific markers during early human intervertebral disc development
- Isolation and phenotypic characterisation of human notochordal cells : implications for the development of cell-based therapies for intervertebral disc degeneration
- The Rock inhibitor Immortalizes Rat Nucleus Pulposus and Annulus Fibrosus Cells: Establishment of Intervertebral Disc Cell Lines with Novel Approaches
- Differentiation of Human-Induced Pluripotent Stem Cells (iPSCs) on Laminin-functionalized PEG Hydrogels under Nucleus Pulposus-Like Culture Conditions
- Stem cells sources for intervertebral disc regeneration.
- CD146 defines commitment of cultured annulus fibrosus cells to express a contractile phenotype
- Construction Strategy and Progress of Whole Intervertebral Disc Tissue Engineering
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