Co-culture of cord blood CD34(+) cells with human BM mesenchymal stromal cells enhances short-term engraftment of cord blood cells in NOD/SCID mice.
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Summary
It is suggested that human BM mesenchymal stromal cells enhance in vitro expansion of CB CD34(+) cells and short-term engraftment of expanded CB cells in NOD/SCID mice, which may be valuable in a clinical setting.
- Type
- article
- Published
- 2007-01-01
- Cited by
- 45
- References
- 31
- OpenAlex
- https://openalex.org/W17573609
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24411686
Keywords
Business
References
- Common lymphoid progenitors rapidly engraft and protect against lethal murine cytomegalovirus infection after hematopoietic stem cell transplantation.
- Multi-lineage expansion potential of primitive hematopoietic progenitors: superiority of umbilical cord blood compared to mobilized peripheral blood.
- The murine stromal cell line AFT024 acts specifically on human CD34+CD38- progenitors to maintain primitive function and immunophenotype in vitro.
- Transplantation of unrelated donor umbilical cord blood in 102 patients with malignant and nonmalignant diseases: influence of CD34 cell dose and HLA disparity on treatment-related mortality and survival.
- Cotransplantation of human stromal cell progenitors into preimmune fetal sheep results in early appearance of human donor cells in circulation and boosts cell levels in bone marrow at later time points after transplantation.
- Identification of the haematopoietic stem cell niche and control of the niche size
- Differential growth factor requirement of primitive cord blood hematopoietic stem cell for self-renewal and amplification vs proliferation and differentiation
- Properties of peripheral blood and cord blood stem cells.
- Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice.
- Hematopoietic stem cells expand during serial transplantation in vivo without apparent exhaustion.
- Characterization of Multipotent Adult Progenitor Cells, a Subpopulation of Mesenchymal Stem Cells
- Biology of Human Umbilical Cord Blood‐Derived Hematopoietic Stem/Progenitor Cells
- Myeloid progenitors protect against invasive aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation.
- Dissociation between stem cell phenotype and NOD/SCID repopulating activity in human peripheral blood CD34(+) cells after ex vivo expansion.
- Osteoblastic cells regulate the haematopoietic stem cell niche
- Immortalized Multipotential Mesenchymal Cells and the Hematopoietic Microenvironment
- Mesenchymal Stem Cells and Hematopoietic Stem Cell Transplantation
- Serum-free coculture system for ex vivo expansion of human cord blood primitive progenitors and SCID mouse-reconstituting cells using human bone marrow primary stromal cells.
- Cytokine expression by human marrow‐derived mesenchymal progenitor cells in vitro: Effects of dexamethasone and IL‐1α
- In vitro and in vivo evidence for the long-term multilineage (myeloid, B, NK, and T) reconstitution capacity of ex vivo expanded human CD34(+) cord blood cells.
Cited by
- Microenvironmental control in microfluidic bioreactors for long term culture of bone marrow cells
- In vitro migratory aberrancies of mesenchymal stem cells derived from multiple myeloma patients only partially modulated by bortezomib.
- Mesenchymal Stem Cells Secreting Angiopoietin-Like-5 Support Efficient Expansion of Human Hematopoietic Stem Cells Without Compromising Their Repopulating Potential
- Defining the identity of human adipose-derived mesenchymal stem cells.
- Advances in umbilical cord blood stem cell expansion and clinical translation.
- Preclinical transplantation and safety of HS/PCs expanded from human umbilical cord blood.
- Perivascular support of human hematopoietic stem/progenitor cells.
- Endothelial cells provide a niche for placental hematopoietic stem/progenitor cell expansion through broad transcriptomic modification.
- Individual and combined effects of mesenchymal stromal cells and recombinant stimulatory cytokines on the in vitro growth of primitive hematopoietic cells from human umbilical cord blood.
- Functional Characterization of TPO‐Expanded CD34+ Cord Blood Cells Identifies CD34−CD61− Cells as Platelet‐Producing Cells Early After Transplantation in NOD/SCID Mice and rCD34+ Cells as CAFC Colony‐Forming Cells
- Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages
- The potential of cytotherapeutics in hematologic reconstitution and in the treatment and prophylaxis of graft-versus-host disease. Chapter II: emerging transformational cytotherapies.
- Cotransplantation of ex vivo expanded and unexpanded cord blood units in immunodeficient mice using insulin growth factor binding protein-2-augmented mesenchymal cell cocultures.
- Co-culture of hematopoietic stem cells with mesenchymal stem cells increases VCAM-1-dependent migration of primitive hematopoietic stem cells
- Concise Review: Ex Vivo Expansion of Cord Blood‐Derived Hematopoietic Stem and Progenitor Cells: Basic Principles, Experimental Approaches, and Impact in Regenerative Medicine
- Current Strategies to Improve Engraftment in Cord Blood Transplantation
- Improving Engraftment and Immune Reconstitution in Umbilical Cord Blood Transplantation
- Comparative analysis of gene transcripts for cell signaling receptors in bone marrow-derived hematopoietic stem/progenitor cell and mesenchymal stromal cell populations
- Combination of low O2 concentration and mesenchymal stromal cells during culture of cord blood CD34+ cells improves the maintenance and proliferative capacity of hematopoietic stem cells
- Mesenchymal stem cell: keystone of the hematopoietic stem cell niche and a stepping-stone for regenerative medicine.
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