MiR-146a-5p promotes IL-1β-induced chondrocyte apoptosis through the TRAF6-mediated NF-kB pathway
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Summary
This work showed that miR-146 induces chondrocyte apoptosis by targeting the TRAF6-mediated NF-KB signaling pathway, and mi-146 may be a potential target for OA treatment.
- Type
- article
- Published
- 2020-04-23
- Cited by
- 60
- References
- 39
- OpenAlex
- https://openalex.org/W3019304017
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:216085366
Keywords
Chondrocyte, Western blot, Apoptosis, microRNA, Transfection
References
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- Efficacy of Platelet-Rich Plasma in the Treatment of Knee Osteoarthritis: A Meta-analysis of Randomized Controlled Trials.
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Cited by
- Potential of zebrafish as a model to characterise MicroRNA profiles in mechanically mediated joint degeneration
- Upregulated ox40l Can Be Inhibited by miR-146a-5p in Condylar Chondrocytes Induced by IL-1β and TNF-α: A Possible Regulatory Mechanism in Osteoarthritis
- Effects of miR-146a-5p on chondrocyte interleukin-1β-induced inflammation and apoptosis involving thioredoxin interacting protein regulation
- Molecular cargo in myeloid-derived suppressor cells and their exosomes
- Toxoplasma gondii Chinese 1 Genotype Wh6 Strain Causes Mice Abnormal Cognitive Behavior through Affecting Hippocampal Neurons
- Exosomes from mesenchymal stem cells expressing microribonucleic acid-125b inhibit the progression of diabetic nephropathy via the tumour necrosis factor receptor-associated factor 6/Akt axis.
- MicroRNA Sequences Modulated by Beta Cell Lipid Metabolism: Implications for Type 2 Diabetes Mellitus
- MicroRNA-489-3p promotes adipogenesis by targeting the Postn gene in 3T3-L1 preadipocytes.
- Exosomes Derived from miR-146a-5p-Enriched Mesenchymal Stem Cells Protect the Cardiomyocytes and Myocardial Tissues in the Polymicrobial Sepsis through Regulating MYBL1
- Bioinformatics analysis and experimental validation of differentially expressed genes in mouse articular chondrocytes treated with IL-1β using microarray data
- Positive feedback loop of lncRNA FAM201A/miR-146a-5p/POU2F1 regulates IL-1β-induced chondrocyte injury in vitro
- Crosstalk Among circRNA/lncRNA, miRNA, and mRNA in Osteoarthritis
- A review of non-coding RNA related to NF-κB signaling pathway in the pathogenesis of osteoarthritis.
- Confirmation of inhibitingTLR4/MyD88/NF-κB Signalling Pathway by Duhuo Jisheng Decoction on Osteoarthritis: A Network Pharmacology Approach-Integrated Experimental Study
- Long Noncoding RNA SLC20A1-1 Induces Nucleus Pulposus Apoptosis by Sponging miR-146a-5p
- MiR-146a expression profiles in osteoarthritis in different tissue sources: a meta-analysis of observational studies
- Zw10 negatively regulates the MyD88-mediated NF-κB signaling through autophagy in teleost fish.
- The lncRNA PRINS-miRNA-mRNA Axis Gene Expression Profile as a Circulating Biomarker Panel in Psoriasis
- Synovial Fluid Regulates the Gene Expression of a Pattern of microRNA via the NF-κB Pathway: An In Vitro Study on Human Osteoarthritic Chondrocytes
- Lupus nephritis: The regulatory interplay between epigenetic and MicroRNAs
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