MiR-146a expression profiles in osteoarthritis in different tissue sources: a meta-analysis of observational studies
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Summary
The expression level of miR-146a in cartilage tissue and PBMCs was significantly higher in OA patients than in non-OA healthy controls and in synovial tissue,synovial fluid, and regulatory T cells, there was no significant difference.
- Type
- review
- Published
- 2022-03-05
- Cited by
- 18
- References
- 53
- Access
- Open access
- OpenAlex
- https://openalex.org/W4220943924
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:247233169
Keywords
Medicine, Osteoarthritis, Synovial fluid, Internal medicine, Peripheral blood mononuclear cell
References
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- MicroRNA 146a Expression in Rheumatoid Arthritis: Association with Tumor Necrosis Factor-Alpha and Disease Activity
- Histone deacetylase inhibitors increase microRNA-146a expression and enhance negative regulation of interleukin-1β signaling in osteoarthritis fibroblast-like synoviocytes.
- Circulating MicroRNAs as a Novel Class of Diagnostic Biomarkers in Gastrointestinal Tumors Detection: A Meta-Analysis Based on 42 Articles
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- Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis
- Comparative performance of heterogeneity variance estimators in meta‐analysis: a review of simulation studies
- Expression of miR-146a, miR-155, and miR-223 in formalin-fixed paraffin-embedded synovial tissues of patients with rheumatoid arthritis and osteoarthritis
- Micro RNA-146a expression, NF-κB/P65 activity and serum pentosidine levels as potential biomarkers for disease severity in primary knee osteoarthritis patients
- Hypoxia-induced microRNA-146a represses Bcl-2 through Traf6/IRAK1 but not Smad4 to promote chondrocyte autophagy
- Hydrostatic Pressure Regulates MicroRNA Expression Levels in Osteoarthritic Chondrocyte Cultures via the Wnt/β-Catenin Pathway
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- MiRNA expression in the cartilage of patients with osteoarthritis
Cited by
- Synovial Fluid Regulates the Gene Expression of a Pattern of microRNA via the NF-κB Pathway: An In Vitro Study on Human Osteoarthritic Chondrocytes
- Temporal transcriptomic changes in microRNAs involved in the host immune response and metabolism during Neospora caninum infection
- MicroRNA expression in osteoarthritis: a meta-analysis
- MicroRNA as Possible Mediators of the Synergistic Effect of Celecoxib and Glucosamine Sulfate in Human Osteoarthritic Chondrocyte Exposed to IL-1β
- Comprehensive bioinformatics analysis of key miRNAs and signaling pathways in the body fluids of human knee osteoarthritis.
- Indirect influence of microRNA‐146a on the association of IL‐6 and TNF‐α genetic polymorphisms with the increased risk of hip osteoarthritis
- Intraarticular treatment with integrin α10β1-selected mesenchymal stem cells affects microRNA expression in experimental post-traumatic osteoarthritis in horses
- The Role of MicroRNAs in the Pathophysiology of Osteoarthritis
- Immunomodulation and fibroblast dynamics driving nociceptive joint pain within inflammatory synovium: Unravelling Mechanisms for Therapeutic Advancements in Osteoarthritis.
- Application of kartogenin for the treatment of cartilage defects: current practice and future directions
- Regulation of ferroptosis in osteoarthritis and osteoarthritic chondrocytes by typical MicroRNAs in chondrocytes
- A scoping review of statistical methods to investigate colocalization between genetic associations and microRNA expression in osteoarthritis
- MiR203a-3p as a potential biomarker for synovial pathology associated with osteoarthritis: a pilot study
- EZH2/miR-142-3p/HMGB1 axis mediates chondrocyte pyroptosis by regulating endoplasmic reticulum stress in knee osteoarthritis
- Role of lncRNA XIST/miR-146a Axis in Matrix Degradation and Apoptosis of Osteoarthritic Chondrocytes Through Regulation of MMP-13 and BCL2
- MicroRNA-146a-3p as an alternative to anti-IL-6 monoclonal antibody therapy: Intra-articular liposome delivery for osteoarthritis treatment
- Synovial Fluid and Serum MicroRNA Signatures in Equine Osteoarthritis
- The Obesogenic Joint Revisited: Mechanobiological, Microbial, and Epigenetic Interfaces in the Pathogenesis of Early-Onset Osteoarthritis
- MicroRNA as Possible Mediators of the Synergistic Effect of Celecoxib and Glucosamine Sulfate in Human Osteoarthritic Chondrocyte Exposed to IL-1β
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