Toll-like Receptors and the control of immunity
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Summary
The mechanisms and consequences of TLR-mediated signal transduction are described, with a focus on themes identified in the TLR pathways that also explain the operation of other immune signaling pathways.
- Type
- review
- Published
- 2020-03-01
- Cited by
- 1,847
- References
- 272
- Access
- Open access
- OpenAlex
- https://openalex.org/W3012283572
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:212656720
Keywords
Biology, Signal transduction, Innate immune system, Receptor, Immunity
References
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- Cutting Edge: A Natural Antisense Transcript, AS-IL1α, Controls Inducible Transcription of the Proinflammatory Cytokine IL-1α
- Crystal structure of the C-terminal domain of mouse TLR9
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- The mechanisms behind heatstroke-induced intestinal damage
- Targeting TLR4-dependent inflammation in post-hemorrhagic brain injury
- COVID-19 pandemic: is a gender-defined dosage effect responsible for the high mortality rate among males?
- Dietary milk fat globule membrane supplementation during late gestation increased the growth of neonatal piglets by improving their plasma parameters, intestinal barriers, and fecal microbiota
- Developmentally regulated PERK activity renders dendritic cells insensitive to subtilase cytotoxin-induced integrated stress response
- The association between poverty and gene expression within peripheral blood mononuclear cells in a diverse Baltimore City cohort
- Wdfy1 deficiency impairs Tlr3-mediated immune responses in vivo
- Fourth defence molecule completes antiviral line-up
- COVID 19: a clue from innate immunity
- Organic/inorganic nanocomposites for cancer immunotherapy
- Sustained Immunoparalysis in Endotoxin-Tolerized Monocytic Cells
- Toll-like receptor 7 deficiency mitigates hyperoxia-induced acute lung injury in mice.
- Toll-Like Receptor Characterization Correlates with Asthma and Is Predictive of Diagnosis
- Okra polysaccharide-2 plays a vital role on the activation of RAW264.7 cells by TLR2/4-mediated signal transduction pathways.
- OMV Vaccines and the Role of TLR Agonists in Immune Response
- Host Immune Response and Novel Diagnostic Approach to NTM Infections
- The role of Chloroquine and Hydroxychloroquine in Immune Regulation and Diseases.
- Advances in Understanding the Initial Steps of Pruritoceptive Itch: How the Itch Hits the Switch
- RNA Recognition and Immunity—Innate Immune Sensing and Its Posttranscriptional Regulation Mechanisms
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