Crucial Players in Glycolysis: Cancer Progress.
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Summary
The main genes, enzymes and factors are begun to investigate and further studied for understanding their roles in metabolism of cancer cells.
- Type
- review
- Published
- 2020-02-05
- Cited by
- 201
- References
- 33
- OpenAlex
- https://openalex.org/W2980982934
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:204814199
Keywords
Warburg effect, Glycolysis, Biology, Cancer cell, Cancer
References
- By reducing hexokinase 2, resveratrol induces apoptosis in HCC cells addicted to aerobic glycolysis and inhibits tumor growth in mice
- The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
- Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth
- PKM2 isoform-specific deletion reveals a differential requirement for pyruvate kinase in tumor cells
- Glycolytic genes in cancer cells are more than glucose metabolic regulators
- AMPK - a nutrient and energy sensor that maintains energy homeostasis
- How do glycolytic enzymes favour cancer cell proliferation by nonmetabolic functions?
- Role of p53 in Cell Death and Human Cancers
- The Warburg effect in 2012
- Diet and food resource partitioning in koaro, Galaxias brevipinnis (Günther), and juvenile rainbow trout, Oncorhynchus mykiss (Richardson), in two Taupo streams, New Zealand
- HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O2 Sensing
- Mitochondrial Binding of Hexokinase II Inhibits Bax-induced Cytochrome c Release and Apoptosis*
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
- Hypoxia-inducible nuclear factors bind to an enhancer element located 3' to the human erythropoietin gene.
- TIGAR, a p53-inducible regulator of glycolysis and apoptosis.
- Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme
- Inhibition of glycolysis in cancer cells: a novel strategy to overcome drug resistance associated with mitochondrial respiratory defect and hypoxia.
- Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O2-Regulated Prolyl Hydroxylation
- c-Myc and Cancer Metabolism
Cited by
- Sinomenine Inhibits Non-Small Cell Lung Cancer via Downregulation of Hexokinases II-Mediated Aerobic Glycolysis
- Knockdown of KRT17 decreases osteosarcoma cell proliferation and the Warburg effect via the AKT/mTOR/HIF1α pathway
- Insights into the New Cancer Therapy through Redox Homeostasis and Metabolic Shifts
- Metastasis of Uveal Melanoma with Monosomy-3 Is Associated with a Less Glycogenetic Gene Expression Profile and the Dysregulation of Glycogen Storage
- TWIST1-overexpression induces glycolytic reprogramming and ATP production in 293T cells
- Puerarin Inhibits the Progression of Bladder Cancer by Regulating circ_0020394/miR-328-3p/NRBP1 Axis
- Circ_0004913 Inhibits Cell Growth, Metastasis, and Glycolysis by Absorbing miR-184 to Regulate HAMP in Hepatocellular Carcinoma
- Identification of circ_0085616 as an Upregulated and Oncogenic Circular RNA in Cervical Cancer Via the miR-503-5p-Mediated ATXN7L3 Activation
- Prognostic model of invasive ductal carcinoma of the breast based on differentially expressed glycolysis-related genes
- Thrombospondin 2/Toll-Like Receptor 4 Axis Contributes to HIF-1α-Derived Glycolysis in Colorectal Cancer
- Circular RNA circSEMA5A promotes bladder cancer progression by upregulating ENO1 and SEMA5A expression
- miR-218 inhibits glucose metabolism in non-small cell lung cancer via the NF-κB signaling pathway.
- Domesticated and optimized mitochondria: Mitochondrial modifications based on energetic status and cellular stress.
- A glycolysis-based three-gene signature predicts survival in patients with lung squamous cell carcinoma
- Diethyldithiocarbamate-copper complex (CuET) inhibits colorectal cancer progression via miR-16-5p and 15b-5p/ALDH1A3/PKM2 axis-mediated aerobic glycolysis pathway
- Glycolysis-Related Genes Serve as Potential Prognostic Biomarkers in Clear Cell Renal Cell Carcinoma
- Effects of the Novel PFKFB3 Inhibitor KAN0438757 on Colorectal Cancer Cells and Its Systemic Toxicity Evaluation In Vivo
- Circ-BANP Contributes to Cell Carcinogenesis and Aerobic Glycolysis by Regulating MAPK1 Through miR-874-3p in Colorectal Cancer
- Elevated TEFM expression promotes growth and metastasis through activation of ROS/ERK signaling in hepatocellular carcinoma
- Mechanisms of Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation
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