AMPK - a nutrient and energy sensor that maintains energy homeostasis

Keywords

AMPK, Energy homeostasis, Cell biology, Catabolism, Protein kinase A

References

• Berberine, a Natural Plant Product, Activates AMP-Activated Protein Kinase With Beneficial Metabolic Effects in Diabetic and Insulin-Resistant StatesHongming Liu, Lizhang Qin, Xiaoping Jia — 2006
• The energy sensing LKB1–AMPK pathway regulates p27kip1 phosphorylation mediating the decision to enter autophagy or apoptosis刘瓦林, 沈冬, 宋坪 — 2007
• Regulation of HMG‐CoA reductase: identification of the site phosphorylated by the AMP‐activated protein kinase in vitro and in intact rat liver.Paul R. Clarke, D. Grahame Hardie — 1990
• Diurnal rhythm of phosphorylation of rat liver acetyl-CoA carboxylase by the AMP-activated protein kinase, demonstrated using freeze-clamping. Effects of high fat diets.Stephen Davies, David Carling, Michael R. Munday — 1992
• Evidence for a protein kinase cascade in higher plants. 3-Hydroxy-3-methylglutaryl-CoA reductase kinase.Robert W. MacKintosh, Stephen Davies, Paul R. Clarke — 1992
• AMP-activated protein kinase is activated by low glucose in cell lines derived from pancreatic beta cells, and may regulate insulin release.Ian P. Salt, Gabriele JOHNSON, Stephen J.H. Ashcroft — 1998
• Common variants near ATM are associated with glycemic response to metformin in type 2 diabetesKaixin Zhou, Céline Bellenguez, Chris C. A. Spencer — 2010
• Metabolic control through the PGC-1 family of transcription coactivators.Jiandie D. Lin, Christoph Handschin, Bruce M. Spiegelman — 2005
• Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK ActivationSimon A. Hawley, Fiona A. Ross, Cyrille Chevtzoff — 2010
• Hispidulin potently inhibits human glioblastoma multiforme cells through activation of AMP-activated protein kinase (AMPK).Yingchao Lin, Chao‐Ming Hung, Jia-Chun Tsai — 2010
• AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1Joungmok Kim, Mondira Kundu, Benoı̂t Viollet — 2011
• The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor*Eric Lieberman Greer, Philip R. Oskoui, Max R. Banko — 2007
• Glucose repression/derepression in budding yeast: SNF1 protein kinase is activated by phosphorylation under derepressing conditions, and this correlates with a high AMP:ATP ratio.Wayne A. Wilson, Simon A. Hawley, D. Grahame Hardie — 1996
• 5′-AMP Activates the AMP-activated Protein Kinase Cascade, and Ca2+/Calmodulin Activates the Calmodulin-dependent Protein Kinase I Cascade, via Three Independent Mechanisms (*)Simon A. Hawley, Michele A. Selbert, Elaine G. Goldstein — 1995
• The structure of a domain common to archaebacteria and the homocystinuria disease protein.Alex Bateman — 1997
• An antibody VH domain with a lox‐Cre site integrated into its coding region: bacterial recombination within a single polypeptide chainJulian Davies, Lutz Riechmann — 1995
• Characterization of the AMP-activated Protein Kinase Kinase from Rat Liver and Identification of Threonine 172 as the Major Site at Which It Phosphorylates AMP-activated Protein Kinase*Simon A. Hawley, Matt Davison, Angela Woods — 1996
• Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibitionCheng Ji, Bang‐Hung Yang, Y-L Yang — 2010
• The Anti-diabetic Drugs Rosiglitazone and Metformin Stimulate AMP-activated Protein Kinase through Distinct Signaling Pathways*Lee G.D. Fryer, Asha Parbhu Patel, David Carling — 2002
• Ionizing radiation induces ataxia telangiectasia mutated kinase (ATM)-mediated phosphorylation of LKB1/STK11 at Thr-366.Gopal P. Sapkota, Mária Deák, Agnieszka Kieloch — 2002

Cited by

• Vigna nakashimae Extract Prevents Hepatic Steatosis in Obese Mice Fed High-Fat DietsYonghae Son, Min Kyung Jang, Myeong Ho Jung — 2014
• Frailty Attenuates the Impact of Metformin on Reducing Mortality in Older Adults with Type 2 DiabetesChen‐Pin Wang, Carlos Lorenzo, Sara Espinoza — 2014
• Metformin is synthetically lethal with glucose withdrawal in cancer cellsJosé Luis Maya — 2012
• Bmf upregulation through the AMP-activated protein kinase pathway may protect the brain from seizure-induced cell deathVictor Igreja — 2013
• Oxygen Sensing by the Carotid Body: Is It All Just Rotten Eggs?Paul J. Kemp, Vsevolod Telezhkin — 2014
• Hypoxia and metabolism in cancer.Priya Gothwal, Ila Shukla — 2014
• The transcriptional coactivator PGC-1α is dispensable for chronic overload-induced skeletal muscle hypertrophy and metabolic remodelingPatricia Trubl — 2013
• Insulin/insulin-like growth factor signaling in C. elegans.Rachmat Mudiyono, Hasanan Md. Nor, Tung Chai Ling — 2013
• Decoding Insulin Resistance and Metabolic Syndrome for Promising Therapeutic InterventionМешкова Ольга Владимировна — 2014
• Metabolic Influences That Regulate Dendritic Cell Function in TumorsElizabeth Griffin — 2014
• Metformin interferes with bile acid homeostasis through AMPK-FXR crosstalk.Courtney Julia — 2014
• Energy and motion: AMP‐activated protein kinase α1 and its role in platelet activationIbrahim Elnasri — 2014
• Neuroprotective Role of Trans-Resveratrol in a Murine Model of Familial Alzheimer's DiseaseDebaprasad Bandyopadhyay — 2014
• Energy metabolism and metabolic sensors in stem cells: the metabostem crossroads of aging and cancer.Jonathan Cimino, Nor Eddine Sounni, David Calligaris — 2014
• Mild Electrical Stimulation Increases Stress Resistance and Suppresses Fat Accumulation via Activation of LKB1-AMPK Signaling Pathway in C. elegansJ. P. Ros, E. Castillo, Pedro Lorite — 2014
• Metabolism of Skin-Absorbed Resveratrol into Its Glucuronized Form in Mouse SkinMelissa Schnyder — 2014
• Characterization of ghrelin‐sensitive neurons in the lumbosacral defecation center in ratsKiyotada Naitou, Takahiko Shiina, Rintaro Sugita — 2015
• OM2, a Novel Oligomannuronate-Chromium(III) Complex, Promotes Mitochondrial Biogenesis and Lipid Metabolism in 3T3-L1 Adipocytes via the AMPK-PGC1α PathwayКрылов Александр Игоревич — 2015
• Current Understanding of Metformin Effect on the Control of Hyperglycemia in Diabetes朋之 楠田, 康文 今井, 明秀 才本 — 2016
• The Effect of Hippocampal Cognitive Impairment and XIAP on Glucose and Lipids Metabolism in RatsChunbo Xia, Lin Zhu, Wenhua Shao — 2016

Related papers

• The role of the AMP-activated protein kinase in the regulation of energy homeostasis.David Carling — 2007
• AMP-Activated Protein Kinase – A Ubiquitous Signalling Pathway with Key Roles in the Cardiovascular SystemIan P. Salt, D. Grahame Hardie — 2017
• AMP-activated Protein Kinase and Stress ResponsesMou Xiao-y — 2014
• AMPK: a metabolic gauge regulating whole-body energy homeostasis.Ricardo Lage, Carlos Diéguez, Antonio Vidal‐Puig — 2008
• AMP-activated protein kinase, stress responses and cardiovascular diseasesShaobin Wang, Ping Song, Ming-Hui Zou — 2012
• Chutes and Ladders: the search for protein kinases that act on AMPK.Lee A. Witters, Bruce E. Kemp, Anthony R. Means — 2006
• Role of AMP-activated protein kinase in metabolic depression in animalsMark H. Rider — 2015
• A molecular approach to the concerted action of kinases involved in energy homoeostasis.Dietbert Neumann, Uwe Schlattner, Theo Wallimann — 2001
• AMP-activated protein kinase: also regulated by ADP?D. Grahame Hardie, David Carling, S.J. Gamblin — 2011
• Current Evidences and Future Perspectives for AMPK in the Regulation of Milk Production and Mammary Gland BiologyZhihui Wu, Min Tian, Jinghui Heng — 2020