Targeting neurotrophin signaling in cancer: The renaissance
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Summary
Pharmacological interventions against neurotrophin signaling have the potential not only to target cancer cells directly, but also to inhibit neurogenesis and its stimulatory impact on cancer progression and pain.
- Type
- review
- Published
- 2018-09-01
- Cited by
- 92
- References
- 75
- OpenAlex
- https://openalex.org/W2883680686
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:51707240
Keywords
Neurogenesis, Neurotrophin, Neurotrophic factors, Tumor microenvironment, Cancer
References
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- PATHOLOGICAL SPROUTING OF ADULT NOCICEPTORS IN CHRONIC PROSTATE CANCER-INDUCED BONE PAIN
- Oncogenic and drug sensitive NTRK1 rearrangements in lung cancer
- Extracellular cleavage of the p75 neurotrophin receptor is implicated in its pro‐survival effect in breast cancer cells
- Brain-Derived Neurotrophic Factor (BDNF)-Induced Tropomyosin-Related Kinase B (Trk B) Signaling Is a Potential Therapeutic Target for Peritoneal Carcinomatosis Arising from Colorectal Cancer
- Neurotrophins and their receptors stimulate melanoma cell proliferation and migration.
- NTRK3 Is a Potential Tumor Suppressor Gene Commonly Inactivated by Epigenetic Mechanisms in Colorectal Cancer
- Expression of nerve growth factor receptors is correlated with progression and prognosis of human pancreatic cancer
- The Neurobiology of Cancer Pain
Cited by
- The many disguises of the signalling endosome
- Elucidating the mechanisms of psychosocial influences on cancer using preclinical in vivo models
- Tumor Neurobiology and the War of Nerves in Cancer.
- Neurotransmitters: emerging targets in cancer
- The precursor for nerve growth factor (proNGF) is not a serum or biopsy-rinse biomarker for thyroid cancer diagnosis
- Ping-Pong—Tumor and Host in Pancreatic Cancer Progression
- Nerve growth factor (NGF)-TrkA axis in head and neck squamous cell carcinoma triggers EMT and confers resistance to the EGFR inhibitor erlotinib.
- Prolactin (PRL), placenta growth factor (PIGF) and nerve growth factor receptor (NGFR) as biomarkers for early diagnosis and prognosis in patients with esophageal squamous cell carcinoma (ESCC)
- The Multifaceted Role of Heme in Cancer
- Tumour innervation and neurosignalling in prostate cancer
- Nerves in cancer
- Innervation of papillary thyroid cancer and its association with extra-thyroidal invasion
- RNA-Seq profiling of circular RNAs in human small cell lung cancer.
- Ameloblastomas Exhibit Stem Cell Potential, Possess Neurotrophic Properties, and Establish Connections with Trigeminal Neurons
- Immunohistochemical detection of Tyrosine Kinase receptor (TrK) in follicular and plexiform ameloblastoma – A novel study
- Clinicopathological significance of nerves in esophageal cancer.
- Nerve growth factor and its receptor tyrosine kinase TrkA are overexpressed in cervical squamous cell carcinoma
- Whole Transcriptome RNA Sequencing Identified circ_022743, circ_052666, and circ_004452 Were Associated with Colon Cancer Development
- The neuro-immune axis in cancer: relevance of the peripheral nervous system to the disease.
- Low expression of NTF3 is associated with unfavorable prognosis in hepatocellular carcinoma.
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