Computing methods for icosahedral and symmetry-mismatch reconstruction of viruses by cryo-electron microscopy

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Summary

This review summarizes the computational methods for icosahedral and symmetry-mismatch reconstruction of viruses, as well as the likely challenges and bottlenecks in virus reconstruction, such as symmetry mismatch reconstruction, contrast transformation function (CTF) correction, and particle distortion.

Type
article
Published
2018-05-01
Cited by
0
References
55

Keywords

Icosahedral symmetry, Cryo-electron microscopy, Electron microscope, Symmetry (geometry), Microscopy

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