Computing methods for icosahedral and symmetry-mismatch reconstruction of viruses by cryo-electron microscopy
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Summary
This review summarizes the computational methods for icosahedral and symmetry-mismatch reconstruction of viruses, as well as the likely challenges and bottlenecks in virus reconstruction, such as symmetry mismatch reconstruction, contrast transformation function (CTF) correction, and particle distortion.
- Type
- article
- Published
- 2018-05-01
- Cited by
- 0
- References
- 55
- OpenAlex
- https://openalex.org/W2803459516
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:250735211
Keywords
Icosahedral symmetry, Cryo-electron microscopy, Electron microscope, Symmetry (geometry), Microscopy
References
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- IMIRS: a high-resolution 3D reconstruction package integrated with a relational image database.
- Backbone structure of the infectious ε15 virus capsid revealed by electron cryomicroscopy
- Near-atomic resolution reconstructions of icosahedral viruses from electron cryo-microscopy
- Cryo-electron microscopy of viruses
- Procedures for three-dimensional reconstruction of spherical viruses by Fourier synthesis from electron micrographs.
- EMAN: semiautomated software for high-resolution single-particle reconstructions.
- Cryo-EM structures of two bovine adenovirus type 3 intermediates.
- A model-based approach for determining orientations of biological macromolecules imaged by cryoelectron microscopy.
- Identification of the Active Sites in the Methyltransferases of a Transcribing dsRNA Virus
- Near-atomic resolution using electron cryomicroscopy and single-particle reconstruction
- 3.88 Å structure of cytoplasmic polyhedrosis virus by cryo-electron microscopy
- Visualization of a 4-helix bundle in the hepatitis B virus capsid by cryo-electron microscopy
- FREALIGN: high-resolution refinement of single particle structures.
- Three Dimensional Reconstructions of Spherical Viruses by Fourier Synthesis from Electron Micrographs
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