High throughput ANI analysis of 90K prokaryotic genomes reveals clear species boundaries

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Summary

FastANI is developed, a method to compute ANI using alignment-free approximate sequence mapping, and it is shown 95% ANI is an accurate threshold for demarcating prokaryotic species by analyzing about 90,000 proKaryotic genomes.

Type
preprint
Published
2017-11-27
Cited by
5,023
References
44
Access
Open access

Keywords

Genome, Biology, Phylogenetic tree, Pairwise comparison, Computational biology

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