Fast and sensitive protein alignment using DIAMOND
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Summary
DIAMOND is introduced, an open-source algorithm based on double indexing that is 20,000 times faster than BLASTX on short reads and has a similar degree of sensitivity.
- Type
- article
- Published
- 2014-11-17
- Cited by
- 11,995
- References
- 21
- OpenAlex
- https://openalex.org/W2045204781
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:5346781
Keywords
Bottleneck, Metagenomics, Computer science, Diamond, Sensitivity (control systems)
References
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- RAPSearch2: a fast and memory-efficient protein similarity search tool for next-generation sequencing data
- A poor man’s BLASTX—high-throughput metagenomic protein database search using PAUDA
- PatternHunter: faster and more sensitive homology search
- The Human Microbiome Project
- BLAT--the BLAST-like alignment tool.
- Seeds for effective oligonucleotide design
- KEGG: Kyoto Encyclopedia of Genes and Genomes
- Database resources of the National Center for Biotechnology Information
- Search and clustering orders of magnitude faster than BLAST
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