Integrative Analysis of Multi-omics Data for Discovery and Functional Studies of Complex Human Diseases
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Summary
Analytical recommendations for different types of multi-omics data and study designs are provided to guide the emerging multi-omic research, and improvement of the existing analytical methods are suggested.
- Type
- review
- Published
- 2016-01-25
- Cited by
- 346
- References
- 170
- Access
- Open access
- OpenAlex
- https://openalex.org/W2276765849
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:205158558
Keywords
Biology, Computational biology, Omics, Data science, Bioinformatics
References
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- JOINT ANALYSIS OF SNP AND GENE EXPRESSION DATA IN GENETIC ASSOCIATION STUDIES OF COMPLEX DISEASES
- Role of Tet proteins in 5mC to 5hmC conversion, ES cell self-renewal, and ICM specification
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- Advances in Integrating Traditional and Omic Biomarkers When Analyzing the Effects of the Mediterranean Diet Intervention in Cardiovascular Prevention
- Strategies to avoid drowning in the deep sequencing data flood
- Meta-Analysis of Gene Expression Profiles in Acute Promyelocytic Leukemia Reveals Involved Pathways
- Cognitive Functions: Human vs. Animal – 4:1 Advantage |-FAM72–SRGAP2-|
- Multidimensional Integrative Genomics Approaches to Dissecting Cardiovascular Disease
- Multi-omics approaches to disease
- The Potential of Pharmacogenomics to Advance Kidney Disease Treatment.
- Advances in Understanding the Molecular Basis of the Mediterranean Diet Effect.
- Mass-spectrometry-based lipidomics.
- Data Portal for the Library of Integrated Network-based Cellular Signatures (LINCS) program: integrated access to diverse large-scale cellular perturbation response data
- Integration of metabolomics and transcriptomics in nanotoxicity studies
- Perceptions and experiences of early-adopting registered dietitians in integrating nutrigenomics into practice
- Impact of the “Omics Sciences” in Medicine: New Era for Integrative Medicine
- Untargeted metabolomics reveals multiple metabolites influencing smoking-related DNA methylation.
- DNA methylation in human lipid metabolism and related diseases
- Arachidonic Acid Metabolism Pathway Is Not Only Dominant in Metabolic Modulation but Associated With Phenotypic Variation After Acute Hypoxia Exposure
- The High-Throughput Analyses Era: Are We Ready for the Data Struggle?
- regQTLs: Single nucleotide polymorphisms that modulate microRNA regulation of gene expression in tumors
- How Should Biobanks Prioritize and Diversify Biosample Collections? A 40-Year Scientific Publication Trend Analysis by the Type of Biosample
- Systems Biology-based Investigation of Host-Plasmodium Interactions
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