Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse.
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Summary
This work used desmin and alpha-smooth muscle actin (ASMA) as markers to analyze vSMC/PC development in PDGF-B-/- and PDGFR-beta-/- embryos and found that endothelial expression of PDGF -B was restricted to immature capillary endothelial cells and to the endothelium of growing arteries.
- Type
- article
- Published
- 1999-07-15
- Cited by
- 1,812
- References
- 36
- OpenAlex
- https://openalex.org/W2169199162
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:2314906
Keywords
Pericyte, Biology, Platelet-derived growth factor receptor, Mural cell, Vascular smooth muscle
References
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- Inhibition of endothelial cell movement by pericytes and smooth muscle cells: activation of a latent transforming growth factor-beta 1-like molecule by plasmin during co-culture
- Blood vessel formation: what is its molecular basis?
- A glioma-derived PDGF A chain homodimer has different functional activities from a PDGF AB heterodimer purified from human platelets.
- Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis.
- The pericyte--a review.
Cited by
- ALK1 et BMP9 dans le remodelage vasculaire de la génétique humaine aux modèles murins
- Comparative study assessing effects of sonic hedgehog and VEGF in a human co-culture model for bone vascularisation strategies.
- Experimental angiogenesis of arterial vasa vasorum
- Lipid mediators of angiogenesis and the signalling pathways they initiate.
- Getting Tie(2)d up in angiogenesis.
- Microglia, macrophages, perivascular macrophages, and pericytes: a review of function and identification
- A new look at platelet-derived growth factor in renal disease.
- Molecular and Cellular Features of Murine Craniofacial and Trunk Neural Crest Cells as Stem Cell-Like Cells
- Plasma MicroRNA Levels Differ between Endurance and Strength Athletes
- Combined Effects of Pericytes in the Tumor Microenvironment
- Rare Coding Variants in ANGPTL6 Are Associated with Familial Forms of Intracranial Aneurysm.
- PEDF expression affects the oxidative and inflammatory state of choroidal endothelial cells.
- PDGF regulated migration of mesenchymal stem cells towards malignancy acts via the PI3K signaling pathway
- Development of Diverse Tools for Pigment Cell Research and Drug Screening in Zebrafish
- Postnatal development of cerebrovascular structure and the neurogliovascular unit
- PDGF-induced coupling of function with metabolism in microvascular pericytes of the retina.
- Angiogenesis and its role in the behavior of astrocytic brain tumors.
- Etude des interfaces sang/cerveau dans la région tubérale de l'hypothalamus médiobasal: rôle des tanycytes de l'éminence médiane.
- Regenerative medicine and tissue engineering- Cells and biomaterials
- PDGF and vessel maturation.
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