Inflammatory links between obesity and metabolic disease.
Explore this paper's citation graph
Summary
This Review highlights the cellular and molecular mechanisms at play in the generation of obesity-induced inflammation and underscores how defining the immune regulation in metabolic tissues has broadened the understanding of the diversity of inflammatory responses.
- Type
- review
- Published
- 2011-06-01
- Cited by
- 2,235
- References
- 120
- Access
- Open access
- OpenAlex
- https://openalex.org/W2165604976
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:26473568
Keywords
Obesity, Inflammation, Disease, Conceptualization, Cognitive reframing
References
- Studies on the Mechanism of Action of Orinase (Tolbutamide)
- Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
- The Effects of Salsalate on Glycemic Control in Patients With Type 2 Diabetes
- Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillbirth in a nonhuman primate model of excess nutrition.
- Principles of bioactive lipid signalling: lessons from sphingolipids
- Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression
- Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.
- Myeloid lineage cell-restricted insulin resistance protects apolipoproteinE-deficient mice against atherosclerosis.
- Postprandial Variations of Plasma Inflammatory Markers in Abdominally Obese Men
- Minireview: Inflammation and obesity pathogenesis: the hypothalamus heats up.
- Inflammation and metabolic disorders
- Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.
- Hypothalamic inflammation and energy homeostasis: resolving the paradox.
- Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes
- Obesity is associated with macrophage accumulation in adipose tissue.
- The NLRP3 Inflammasome: A Sensor for Metabolic Danger?
- Metabolic and Vascular Effects of Tumor Necrosis Factor-α Blockade with Etanercept in Obese Patients with Type 2 Diabetes
- Hematopoietic cell specific deletion of Toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high fat fed mice
- Fat Treg cells: a liaison between the immune and metabolic systems
- Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
Cited by
- C-Reactive Protein Levels in African Americans: A Diet and Lifestyle Randomized Community Trial
- Etude du rôle des sous-populations monocytaires dans l'obésité et l'insulinorésistance
- Cannabinoid signalling regulates inflammation and energy balance: the importance of the brain-gut axis.
- Insulin resistance at diagnosis in Japanese children with type 2 diabetes mellitus
- Obesity: A Transgenerational Problem Linked to Nutrition during Pregnancy
- Start of insulin therapy in patients with type 2 diabetes mellitus promotes the influx of macrophages into subcutaneous adipose tissue
- DIETARY RESTRICTION REVERSES OBESITY-INDUCED ANHEDONIA
- Elevated Endoplasmic Reticulum Stress Response Contributes to Adipose Tissue Inflammation in Aging.
- n-3 Polyunsaturated Fatty Acids and Mechanisms to Mitigate Inflammatory Paracrine Signaling in Obesity-Associated Breast Cancer
- Premorbid obesity and metabolic disturbances as promising clinical targets for the prevention and early screening of bipolar disorder.
- Delivery of Adipose-Derived Stem Cells Attenuates Adipose Tissue Inflammation and Insulin Resistance in Obese Mice Through Remodeling Macrophage Phenotypes
- Lack of mature lymphocytes results in obese but metabolically healthy mice when fed a high-fat diet
- Galectin-3 Ablation Enhances Liver Steatosis, but Attenuates Inflammation and IL-33-Dependent Fibrosis in Obesogenic Mouse Model of Nonalcoholic Steatohepatitis
- Short-term high-intensity interval and moderate-intensity continuous training reduce leukocyte TLR4 in inactive adults at elevated risk of type 2 diabetes.
- Influence of Obesity Diagnosis With Organ Dysfunction, Mortality, and Resource Use Among Children Hospitalized With Infection in the United States
- Hepatocyte TRAF3 promotes insulin resistance and type 2 diabetes in mice with obesity
- Sexually dimorphic myeloid inflammatory and metabolic responses to diet-induced obesity.
- Apolipoprotein A-I gene transfer exerts immunomodulatory effects and reduces vascular inflammation and fibrosis in ob/ob mice
- Exercise Training Attenuates the Dysregulated Expression of Adipokines and Oxidative Stress in White Adipose Tissue
- Lipotoxicity in Obesity: Benefit of Olive Oil.
Related papers
- A reframe by any other name: on the process of refraining in strategic, Milan and analytic therapy
- A Study on Case Conceptualization Elements: Focusing on Domestic Research
- Herformulering as pastoraal-terapeutiese konsep
- An empirical analysis into the reframing approach of organisational behaviour
- "Reframing" as an Innovative Educational Technique
- Reframing--reappraising an old behavioral technique.
- Reframing Aging: A Generation's Work