Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
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Summary
It is found that cancer cells had a loss of monoacetylated and trimethylated forms of histone H4 early and accumulated during the tumorigenic process, which is a common hallmark of human tumor cells.
- Type
- article
- Published
- 2005-03-13
- Cited by
- 1,910
- References
- 52
- OpenAlex
- https://openalex.org/W2155725346
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:27245550
Keywords
Biology, Histone, Acetylation, Epigenetics, Histone H4
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- Effects of DNA Methyltransferase- and Histone Deacetylase Inhibitors on ALK Positive Anaplastic Large Cell Lymphoma
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- Prognostic and predictive biomarkers in breast cancer: Past, present and future.
- Investigating higher-order chromatin structure and SAGA cooperativity using existing and modified in vitro chromatin systems
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