Genetic Analysis of Adult-Onset Autoimmune Diabetes
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Summary
The results are consistent with the hypothesis that the genetics of autoimmune diabetes in adults and children are differentiated by only relatively few age-dependent genetic effects.
- Type
- article
- Published
- 2011-09-16
- Cited by
- 150
- References
- 50
- Access
- Open access
- OpenAlex
- https://openalex.org/W2152149724
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1441468
Keywords
PTPN22, Autoantibody, Type 1 diabetes, Medicine, Human leukocyte antigen
References
- Common variants in the TCF7L2 gene help to differentiate autoimmune from non-autoimmune diabetes in young (15–34 years) but not in middle-aged (40–59 years) diabetic patients
- Replication of Genome-Wide Association Signals in UK Samples Reveals Risk Loci for Type 2 Diabetes
- Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes
- FCRL3 -169CT functional polymorphism in type 1 diabetes and autoimmunity traits.
- The functional variant –169C/T in the FCRL3 gene does not increase susceptibility to Type 1 diabetes
- Epidemiology and Immunogenetic Background of Islet Cell Antibody–Positive Nondiabetic Schoolchildren: Ulm-Frankfurt Population Study
- Contribution of single nucleotide polymorphisms within FCRL3 and MAP3K7IP2 to the pathogenesis of Graves' disease.
- Incidence trends for childhood type 1 diabetes in Europe during 1989-2003 and predicted new cases 2005-20: a multicentre prospective registration study.
- Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity
- Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locus
- Prediction and Interaction in Complex Disease Genetics: Experience in Type 1 Diabetes
- T-cell immunosenescence: lessons learned from mouse models of aging
- Latent autoimmune diabetes in adults (LADA) is dead: long live autoimmune diabetes!
- No association of multiple type 2 diabetes loci with type 1 diabetes
- Shared and Distinct Genetic Variants in Type 1 Diabetes and Celiac Disease
- Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin
- An autoimmune-associated variant in PTPN2 reveals an impairment of IL-2R signaling in CD4+ T cells
- Analysis of the Fc receptor-like-3 (FCRL3) locus in Caucasians with autoimmune disorders suggests a complex pattern of disease association.
- Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource
- Associations of GAD65- and IA-2-Autoantibodies With Genetic Risk Markers in New-Onset IDDM Patients and Their Siblings. The Belgian Diabetes Registry
Cited by
- Latent Autoimmune Diabetes in Adults: Current Status and New Horizons
- Allostasis and the origins of adult-onset diabetes
- A study of biomarker analysis in association with type 1 diabetes and their shared features in rheumatoid arthritis
- Transmission disequilibrium analysis of 31 type 1 diabetes susceptibility loci in Finnish families.
- Insulin gene VNTR polymorphisms −2221MspI and −23HphI are associated with type 1 diabetes and latent autoimmune diabetes in adults: a meta-analysis
- Diabetes at the crossroads: relevance of disease classification to pathophysiology and treatment
- Latent autoimmune diabetes of the adult: current knowledge and uncertainty
- HLA class II gene associations in African American Type 1 diabetes reveal a protective HLA-DRB1*03 haplotype
- The Tyrphostin Agent AG490 Prevents and Reverses Type 1 Diabetes in NOD Mice
- Common Variants on Cytotoxic T Lymphocyte Antigen-4 Polymorphisms Contributes to Type 1 Diabetes Susceptibility: Evidence Based on 58 Studies
- Age‐dependent decline of β‐cell function in type 1 diabetes after diagnosis: a multi‐centre longitudinal study
- Population-based and family-based studies on the protein tyrosine phosphatase non-receptor 22 gene polymorphism and type 1 diabetes: a meta-analysis.
- Molecular Mechanisms in Autoimmune Type 1 Diabetes: a Critical Review
- Association of the C-type lectin-like domain family-16A (CLEC16A) gene polymorphisms with acute coronary syndrome in Mexican patients.
- Genetic association of zinc transporter 8 (ZnT8) autoantibodies in type 1 diabetes cases
- Renalase, kidney and cardiovascular disease: are they related or just coincidentally associated?
- Type 1 diabetes
- Genetics of diabetes--are we missing the genes or the disease?
- 12q24 locus association with type 1 diabetes: SH2B3 or ATXN2?
- Genes Involved in Type 1 Diabetes: An Update
Related papers
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