Loss of Functional Suppression by CD4+CD25+ Regulatory T Cells in Patients with Multiple Sclerosis

Keywords

IL-2 receptor, Multiple sclerosis, Peripheral tolerance, Immunology, Biology

References

• The Neuroimmunology of Multiple Sclerosis: Possible Roles of T and B Lymphocytes in Immunopathogenesisしのぶ 飯村, Iimura Shinobu, 藤女子大学人間生活学部人間生活学科藤女子大学大学院人間生活学研究科人間生活学専攻 — 2001
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• Toll Pathway-Dependent Blockade of CD4+CD25+ T Cell-Mediated Suppression by Dendritic CellsChandrashekhar Pasare, Ruslan Medzhitov — 2003
• T cell tolerance by clonal elimination in the thymus.John W. Kappler, Neal W. Roehm, Philippa Marrack — 1987
• Control of T‐cell activation by CD4+ CD25+ suppressor T cellsEthan M. Shevach, Rebecca S. McHugh, Ciriaco A. Piccirillo — 2001
• Regulatory T cellsShimon Sakaguchi — 2006
• B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes.Benoı̂t L. Salomon, Deborah J. Lenschow, Lesley Rhee — 2000
• Decreased dependence of myelin basic protein-reactive T cells on CD28-mediated costimulation in multiple sclerosis patients. A marker of activated/memory T cells.Amy E. Lovett‐Racke, John L. Trotter, Jörg Lauber — 1998
• Role of ICAM-1 and P-selectin expression in the development and effector function of CD4+CD25+regulatory T cells.Adam P. Kohm, Stephen D. Miller — 2003
• Organ-specific autoimmune diseases induced in mice by elimination of T cell subset. I. Evidence for the active participation of T cells in natural self-tolerance; deficit of a T cell subset as a possible cause of autoimmune diseaseShimon Sakaguchi, K Fukuma, Kagemasa Kuribayashi — 1985
• T-cell recognition of an immuno-dominant myelin basic protein epitope in multiple sclerosisKohei Ota, Makoto Matsui, Edgar L. Milford — 1990
• CD4+CD25+ Immunoregulatory T Cells Suppress Polyclonal T Cell Activation In Vitro by Inhibiting Interleukin 2 ProductionAngela M. Thornton, Ethan M. Shevach — 1998
• Inhibition of Human CD4+CD25+high Regulatory T Cell Function1Clare Baecher‐Allan, Vissia Viglietta, David A. Hafler — 2002
• Regulatory T cells in autoimmmunity*.Ethan M. Shevach — 2000
• Ex Vivo Isolation and Characterization of Cd4+Cd25+ T Cells with Regulatory Properties from Human BloodDetlef Dieckmann, Heidi Plöttner, Susanne Berchtold — 2001
• Multiple sclerosis: deeper understanding of its pathogenesis reveals new targets for therapy.Lawrence Steinman, Roland Martinꝉ, Claude C.A. Bernard — 2002
• CD4+CD25+ T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells.Elisabeth Suri‐Payer, Anna Z. Amar, Angela M. Thornton — 1998

Cited by

• Clinical application of human CD4+CD25+ regulatory Tcells for the treatment of inflammatory bowel diseasesRefani Indah Sunurini — 2005
• Contrasting CD25hiCD4+T Cells/FOXP3 Patterns in Chronic Rejection and Operational Drug-Free TolerancePaula A. Monopoli — 2006
• Human regulatory T cells and their role in autoimmune diseaseIldefonso Damas Hurtado — 2006
• Reduced circulating CD4+CD25+ cell populations in Guillain-Barré syndrome.雄一郎 板倉 — 2007
• A CFSE based assay for measuring CD4+CD25+ regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses.Elin Kindberg, Sirkka Vene, Auksė Mickienė — 2007
• Effect of steroids on the frequency of regulatory T cells and expression of FOXP3 in a patient with systemic lupus erythematosus: a two-year follow-up.八十一 田村 — 2007
• Regulatory CD4+CD25+ T cells and macrophages: communication between two regulators of effector T cellsRaquel García Cabrera, Francisco Cabrera López, Luis Rodríguez Melián — 2008
• Phenotypic and Functional Analysis of CD4+CD25−Foxp3+ T Cells in Patients with Systemic Lupus Erythematosus1誠一 奥野, 正幸 小林 — 2009
• Potassium channel expression in human CD4+ regulatory and naïve T cells from healthy subjects and multiple sclerosis patients.María Asunción Barrio Calle — 2009
• CD46 expression and HHV‐6 infection in patients with multiple sclerosisDaniel E. Jones — 2009
• Regulatory T cells: back to the future.Jan Damoiseaux — 2006
• Disturbed regulatory T cell homeostasis in multiple sclerosis.Jorge Isauro, Rionda Ramírez — 2010
• Amelioration of experimental autoimmune encephalitis by novel peptides: involvement of T regulatory cells.Harminder Battu, Heather Brown, Miguel A. Costa‐Gomes — 2010
• Role of CD8+ CD25+ Foxp3+ regulatory T cells in multiple sclerosisJosep Parera — 2009
• Effect of biologic agents on regulatory T cells.Antonio García y García — 2011
• FOXP3, CBLB and ITCH gene expression and cytotoxic T lymphocyte antigen 4 expression on CD4+CD25high T cells in multiple sclerosisJulian Shehu, Fatos Harizaj, Ardian Maçi — 2012
• An IL-27/Lag3 axis enhances Foxp3+ regulatory T cell suppressive function and therapeutic efficacyMalcolm D. Evans — 2015
• Secondary Progression in Multiple Sclerosis: Neuronal Exhaustion or Distinct Pathology?Richard Bégin — 2016
• Cell-Based Therapies with T Regulatory CellsLinda Briskman — 2017
• Association of increased Treg and Th17 with pathogenesis of moyamoya diseaseJavier M.-Tomé Bona — 2017

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