Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination
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Summary
At a given time point of the disease, the patterns of demyelination were heterogeneous between patients, but were homogenous within multiple active lesions from the same patient, suggesting that MS may be a disease with heterogeneous pathogenetic mechanisms.
- Type
- article
- Published
- 2000-06-01
- Cited by
- 3,429
- References
- 45
- OpenAlex
- https://openalex.org/W2147062889
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:14630021
Keywords
Multiple sclerosis, Autoimmunity, Demyelinating disease, Pathology, Myelin
References
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Cited by
- Differenzierte MRT-Befundung zur Diagnosestellung der Multiplen Sklerose
- Genetics of Multiple Sclerosis
- The extracellular matrix in multiple sclerosis: an update.
- Cytokine and IL-12 receptor mRNA discriminate between different clinical subtypes in multiple sclerosis.
- Plasma Factors as Endogenous Agonists and Modulators of TLR4 Signaling in Microglia
- Activity profile in multiple sclerosis: an integrative approach A preliminary report
- Determinants of Human B Cell Migration Across Brain Endothelial Cells1
- Human herpesvirus 6 genome and antigen in acute multiple sclerosis lesions.
- Protectieve effecten van T-lymfocyten in MS : Betrokkenheid van LIF
- MRI outcomes in the diagnosis and disease course of multiple sclerosis.
- Tissue preconditioning may explain concentric lesions in Baló's type of multiple sclerosis.
- Heterogeneity of multiple sclerosis: implications for therapy targeting regeneration.
- [Plasma exchange therapy for steroid-unresponsive multiple sclerosis relapses: clinical experience with 16 patients].
- Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis
- Remyelination strategies: New advancements toward a regenerative treatment in multiple sclerosis
- Contrasting potential of nitric oxide and peroxynitrite to mediate oligodendrocyte injury in multiple sclerosis
- Neuromyelitis optica is a variant of multiple sclerosis.
- Neuromyelitis optica: a distinct demyelinating disease of the central nervous system
- Getting specific: monoclonal antibodies in multiple sclerosis.
- Opticospinal multiple sclerosis in Iran.
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