The Danger Model: A Renewed Sense of Self
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Summary
A model of immunity based on the idea that the immune system is more concerned with entities that do damage than with those that are foreign is outlined.
- Type
- article
- Published
- 2002-04-12
- Cited by
- 4,439
- References
- 69
- OpenAlex
- https://openalex.org/W2145736817
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:13615808
Keywords
Epistemology, Cognitive science, Psychology, Computer science, Philosophy
References
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- Genomic DNA Released by Dying Cells Induces the Maturation of APCs1 2
- ‘Actively Acquired Tolerance’ of Foreign Cells
- Stimulation of human gamma delta T cells by nonpeptidic mycobacterial ligands.
- Vasoactive intestinal peptide specifically induces human IgA1 and IgA2 production
- A new analysis of allogeneic interactions.
- The immune system evolved to discriminate infectious nonself from noninfectious self.
- Inhibition of transplant rejection following treatment with anti-B7-2 and anti-B7-1 antibodies.
- An innate sense of danger.
- Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice.
- Decoding the Patterns of Self and Nonself by the Innate Immune System
- Peritransplant tolerance induction in macaques: early events reflecting the unique synergy between immunotoxin and deoxyspergualin.
- Human CD14 mediates recognition and phagocytosis of apoptotic cells
Cited by
- Self, non-self, and danger: a complementary view.
- ADP-ribosylation of P2X7: a matter of life and death for regulatory T cells and natural killer T cells.
- Antivirale Immunantwort und Virus-induzierte Apoptose von Insulin-produzierenden Zellen in der Pathogenese des Typ 1 Diabetes
- Hsp70: anti-apoptotic and tumorigenic protein.
- [The role of Toll-like receptors (TLR) in innate and adaptive immune responses and their function in immune response regulation].
- Altered Expression of Genes Associated with Innate Immunity and Inflammation in Recalcitrant Rhinosinusitis with Polyps
- Making and breaking tolerance.
- Analysis of the B‐cell repertoire against antigens expressed by human neoplasms
- Polymorphonuclear Granulocytes Induce Antibody-Dependent Apoptosis in Human Breast Cancer Cells1
- Immunogenicity in peptide-immunotherapy: from self/nonself to similar/dissimilar sequences.
- DNA immunisation with minimalistic expression constructs.
- Dynamics of T cell activation threshold tuning.
- Bacterial Ghosts Are an Efficient Delivery System for DNA Vaccines1
- Intravenous Infusion of Syngeneic Apoptotic Cells by Photopheresis Induces Antigen-Specific Regulatory T Cells 1
- siRNA Produced by Recombinant Dicer Mediates Efficient Gene Silencing in Islet Cells
- Tumor immunology, immunomics and targeted immunotherapy for central nervous system malignancies
- B cell abnormality and autoimmune disorders
- Pro-apoptotic DNA vaccination ameliorates new onset of autoimmune diabetes in NOD mice and induces foxp3+ regulatory T cells in vitro.
- [Drug-induced liver injury].
- The innate host defence against nematode parasites
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