Peritransplant tolerance induction in macaques: early events reflecting the unique synergy between immunotoxin and deoxyspergualin.
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Summary
The study suggests DSG arrests dendritic cell maturation, and the unusual synergy of immunotoxin and DSG apparently involves coincidental reduction in lymph node T cell mass and mature DC, a transient circumstance favoring development of stable tolerance.
- Published
- 1999-12-15
- Cited by
- 144
- References
- 64
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:42265045
References
- Deoxyspergualin inhibits kappa light chain expression in 70Z/3 pre-B cells by blocking lipopolysaccharide-induced NF-kappa B activation.
- Immunosuppressant deoxyspergualin inhibits antigen processing in monocytes.
- Functional interaction between TGF-beta and IL-12 in human primary allogeneic cytotoxicity and proliferative response.
- Dendritic cells and the control of immunity
- Total lymphoid irradiation in kidney and liver transplantation in the baboon: prolonged graft survival and alterations in T cell subsets with low cumulative dose regimens.
- Neonatal tolerance induction by class II alloantigens activates IL-4-secreting, tolerogen-responsive T cells.
- Bone marrow chimerism and transplantation tolerance.
- ‘Actively Acquired Tolerance’ of Foreign Cells
- Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys.
- Origin, maturation and antigen presenting function of dendritic cells.
- Prolongation of rat islet allograft survival by direct ultraviolet irradiation of the graft.
- Mixed Allogeneic Chimerism And Renal Allograft Tolerance In Cynomolgus Monkeys
- 15‐Deoxyspergualin: A Novel Immunosuppressive Drug with Clinical Potential a
- 15‐DEOXYSPERGUALIN FOR INDUCTION OF GRAFT NONREACTIVITY AFTER CARDIAC AND RENAL ALLOTRANSPLANTATION IN PRIMATES
- Balancing the immune system for tolerance: a case for regulatory CD4 cells.
- Acute rejection of vascularized heart allografts in the absence of IFNgamma.
- Elucidating the Mechanism of Action of the Immunosuppressant 15‐Deoxyspergualin
- The effect of anti-CD3-immunotoxin on T lymphocyte function in vitro.
- IMMUNOLOGIC RELATIONSHIPS BETWEEN SKIN AND KIDNEY HOMOGRAFTS IN DOGS ON IMMUNOSUPPRESSIVE THERAPY
- Early events controlling T-helper cell differentiation: the role of the IL-12 receptor.
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- Stable α‐ and β‐Islet Cell Function After Tolerance Induction to Pancreatic Islet Allografts in Diabetic Primates
- Treatment of active lupus nephritis with the novel immunosuppressant 15-deoxyspergualin: an open-label dose escalation study
- Induction of tolerogenic dendritic cells by vitamin D receptor agonists.
- Islet Transplantation in Patients with Diabetes Mellitus
- Current and Future Immunosuppressive Therapies Following Transplantation
- Immunological Tolerance
- Dendritic Cells: Tools and Targets for Transplant Tolerance
- Prolongation of liver allograft survival by dendritic cells modified with NF-kappaB decoy oligodeoxynucleotides.
- Dendritic cells,tolerance and therapy of organ allograft rejection.
- Transplant Tolerance in Non‐Human Primates: Progress, Current Challenges and Unmet Needs
- Appropriate targets for monoclonal antibodies in the induction of transplantation tolerance.
- Achieving Donor-Specific Hyporesponsiveness Is Associated with FOXP3+ Regulatory T Cell Recruitment in Human Renal Allograft Infiltrates1
- Induction of tolerance in clinical kidney transplantation
- Alemtuzumab (Campath‐1H) in Kidney Transplantation
- Inhibitory Feedback Loop Between Tolerogenic Dendritic Cells and Regulatory T Cells in Transplant Tolerance 1
- Lymphocyte Activation Markers in Pediatric Kidney Transplant Recipients
- Dendritic cell therapy for Type 1 diabetes suppression.
- CMRF-44 antibody-mediated depletion of activated human dendridic cells: a potential means for improving allograft survival1
- Potential of tolerogenic dendritic cells for transplantation.
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