Regulatory T Cells: Mechanisms of Differentiation and Function
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- Type
- review
- Published
- 2012-01-06
- Cited by
- 2,811
- References
- 238
- Access
- Open access
- OpenAlex
- https://openalex.org/W2141649011
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:207582842
Keywords
Biology, Immune system, FOXP3, Inflammation, Immunology
References
- The role of TCR specificity in naturally arising CD25+ CD4+ regulatory T cell biology.
- Transplantation of T cell-mediated, lymphoreticular disease from the scurfy (sf) mouse.
- Biology of interleukin-2
- The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
- T-cell development and the CD4–CD8 lineage decision
- Cutting edge: lymphoproliferative disease in the absence of CTLA-4 is not T cell autonomous.
- X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy
- Cutting Edge: The Phosphoinositide 3-Kinase p110δ Is Critical for the Function of CD4+CD25+Foxp3+ Regulatory T Cells1
- Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide
- Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism1
- Adaptation of TCR Repertoires to Self-Peptides in Regulatory and Nonregulatory CD4+ T Cells1
- Distinct Effects of STAT5 Activation on CD4+ and CD8+ T Cell Homeostasis: Development of CD4+CD25+ Regulatory T Cells versus CD8+ Memory T Cells 1
- Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse
- Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo
- Analysis of FOXP3 Reveals Multiple Domains Required for Its Function as a Transcriptional Repressor1
- TGF-β Requires CTLA-4 Early after T Cell Activation to Induce FoxP3 and Generate Adaptive CD4+CD25+ Regulatory Cells1
- Cutting Edge: IL-2 Is Essential for TGF-β-Mediated Induction of Foxp3+ T Regulatory Cells
- OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset [published erratum appears in J Exp Med 1991 Apr 1;173(4):1037]
- IL-2 Receptor β-Dependent STAT5 Activation Is Required for the Development of Foxp3+ Regulatory T Cells1
- c-Rel Is Required for Chromatin Remodeling Across the IL-2 Gene Promoter
Cited by
- Mechanism of natural killer cell mediated T cell cycle arrest during human parainfluenza virus type 3 infection
- Transcription factor Foxp3 and its protein partners form a complex regulatory network
- Pregnancy imprints regulatory memory that sustains anergy to fetal antigen
- Adipose tissue‐resident regulatory T cells: phenotypic specialization, functions and therapeutic potential
- Cytokine profiles by peripheral blood monocytes are associated with changes in behavioral symptoms following immune insults in a subset of ASD subjects: an inflammatory subtype?
- Treg cells mediate recovery from EAE by controlling effector T cell proliferation and motility in the CNS
- Chimeric antigen receptors and bispecific antibodies to retarget T cells in pediatric oncology
- Galectin-8 Ameliorates Murine Autoimmune Ocular Pathology and Promotes a Regulatory T Cell Response
- Hypoxia-inducible factors in T lymphocyte differentiation and function. A Review in the Theme: Cellular Responses to Hypoxia.
- Control of Foxp3 stability through modulation of TET activity
- A novel differentiation pathway from CD4+ T cells to CD4− T cells for maintaining immune system homeostasis
- Allergies - A T cells perspective in the era beyond the TH1/TH2 paradigm.
- Tumour‐associated changes in intestinal epithelial cells cause local accumulation of KLRG1+ GATA3+ regulatory T cells in mice
- Unusual Suspects in the Development of Obesity-Induced Inflammation and Insulin Resistance: NK cells, iNKT cells, and ILCs
- Serum miR‐146a, miR‐155, and miR‐210 as potential markers of Graves’ disease
- Programmed death one homolog maintains the pool size of regulatory T cells by promoting their differentiation and stability
- Induction of immunosuppressive CD8+CD25+FOXP3+ regulatory T cells by suboptimal stimulation with staphylococcal enterotoxin C1
- FoxP3 scanning mutagenesis reveals functional variegation and mild mutations with atypical autoimmune phenotypes
- Association of two FOXP3 polymorphisms with breast cancer susceptibility in Chinese Han women
- Antigen-specific regulatory T-cell responses against aeroantigens and their role in allergy
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