The importance of the innate immune system in controlling HIV infection and disease.
Explore this paper's citation graph
Summary
Novel approaches should be developed to elicit this rapidly responding immune activity in HIV infection, and emphasis should now be placed on the alternative arm of the immune system, the innate immune response.
- Type
- review
- Published
- 2001-06-01
- Cited by
- 156
- References
- 56
- OpenAlex
- https://openalex.org/W2141330728
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:45193559
Keywords
Immune system, Innate immune system, Immunology, Acquired immune system, Biology
References
- Contribution of the CCR5 and MBL genes to susceptibility to HIV type 1 infection in the Finnish population.
- HIV-1 gp120-specific antibody-dependent cell-mediated cytotoxicity correlates with rate of disease progression.
- Susceptibility of HIV-1 plasma virus to complement-mediated lysis. Evidence for a role in clearance of virus in vivo.
- Neutralization of human immunodeficiency virus type 1 by complement occurs by viral lysis
- Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytes.
- Preventing AIDS But Not HIV-1 Infection with a DNA Vaccine
- Immunology: A Toll for DNA vaccines
- Natural killer cells from HIV-1+ patients produce C-C chemokines and inhibit HIV-1 infection.
- Suppression of Activation of the Human Immunodeficiency Virus Long Terminal Repeat by CD8+ T Cells Is Not Lentivirus Specific
- Do beta-chemokines have clinical relevance in HIV infection?
- Phosphoantigen-reactive Vgamma9Vdelta2 T lymphocytes suppress in vitro human immunodeficiency virus type 1 replication by cell-released antiviral factors including CC chemokines.
- Brief report: Killer cell defect and persistent immunological abnormalities in two patients with chronic active epstein‐barr virus infection
- CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replication.
- Suppression of human immunodeficiency virus replication by CD8+ cells from infected and uninfected chimpanzees.
- The nature of the principal type 1 interferon-producing cells in human blood.
- Severe herpesvirus infections in an adolescent without natural killer cells.
- The function of type I interferons in antimicrobial immunity.
- CD8+ anti-human immunodeficiency virus suppressor activity (CASA) in response to antiretroviral therapy: loss of CASA is associated with loss of viremia.
- Effects of several species of human leukocyte interferon on cytotoxic activity of NK cells and monocytes
- Deficient polymorphonuclear cell and mononuclear cell antibody-dependent cellular cytotoxicity in pediatric and adult human immunodeficiency virus infection.
Cited by
- Lessons learnt from studies of the immune characterization of naturally SIV infected sooty mangabeys.
- The Relationships between Substance Abuse, Psychosocial Variables, and Natural Killer Cell Enumeration and Function in HIV-Infected and High-Risk Uninfected Adolescents
- GB virus C interactions with HIV: effects on immunoactivation and mechanisms of immunomodulation
- Innovative approaches to develop prophylactic and therapeutic vaccines against HIV/AIDS.
- Multi-layered model of individual HIV infection progression and mechanisms of phenotypical expression
- Selective Depletion of CD56dim NK Cell Subsets and Maintenance of CD56bright NK Cells in Treatment-Naive HIV-1-Seropositive Individuals
- Interactions VIH-hôte : modulation de l'expression de facteurs cellulaires
- Construction and characterization of chimaeric human immunodefiency virus type 1 subtype C Gag virus-like particles
- Therapeutic intervention in inflammatory pathologies and cancer : understanding the anti-inflammatory properties of Viscum album
- The biology of dendritic cells and HIV infection
- HIV-1 strategies to overcome the immune system by evading and invading innate immune system
- Role of Type I IFNs in Pulmonary Complications of Pneumocystis murina Infection 1
- Studies of the pathogenesis of Jembrana disease virus infection in Bos javanicus
- Reacciones y alteraciones del sistema inmune durante la infección por el VIH-1
- NK Cell Activation by Dendritic Cells Is Dependent on LFA-1-Mediated Induction of Calcium-Calmodulin Kinase II: Inhibition by HIV-1 Tat C-Terminal Domain1
- Factores inmunitarios protectivos del huésped contra la infección por el VIH-1 y la progresión a SIDA: quimiocinas y sus receptores.
- Gene expression pattern and functional analysis of CD8+ T cells from individuals with or without anti HIV/SIV noncytolytic activity.
- DYNAMICS OF THE HIV-2-SPECIFIC IMMUNOGLOBULIN A (IgA) RESPONSE
- Evolutionary Models for the Human Immunodeficiency Virus with Applications to Epitope Prediction and the Natural Selection of Escape Variants
- Stimulation of Cell Surface CCR5 and CD40 Molecules by Their Ligands or by HSP70 Up-Regulates APOBEC3G Expression in CD4+ T Cells and Dendritic Cells1
Related papers
- Molecular biology and immunology for clinicians 21: The innate immune system: an introduction.
- From infection to repair: Understanding the workings of our innate immune cells.
- The IL-1 family: regulators of immunity
- Functions of innate immune cells and commensal bacteria in gut homeostasis.
- Advances in immune response to pulmonary infection: Nonspecificity, specificity and memory
- Trained immunity in the mucosal diseases.