MicroRNA gene expression deregulation in human breast cancer.
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Summary
It is shown that, compared with normal breast tissue, miRNAs are also aberrantly expressed in human breast cancer, and the overall miRNA expression could clearly separate normal versus cancer tissues, with the most significantly deregulated mi RNAs being mir-125b, mir-145, mir -21, and mir-155.
- Type
- article
- Published
- 2005-08-15
- Cited by
- 4,264
- References
- 30
- OpenAlex
- https://openalex.org/W2135836598
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:10140281
Keywords
microRNA, Biology, Breast cancer, Gene expression, Cancer
References
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Cited by
- The concept of multiple-target anti-miRNA antisense oligonucleotide technology.
- miRNAs in cancer: approaches, aetiology, diagnostics and therapy.
- Translational Medicine: microRNAs: a new emerging class of players for disease diagnostics and gene therapy
- MicroRNAs in breast cancer
- Genomic profiling of microRNAs in bladder cancer: miR-129 is associated with poor outcome and promotes cell death in vitro.
- Restoration of tumour suppressor hsa-miR-145 inhibits cancer cell growth in lung adenocarcinoma patients with epidermal growth factor receptor mutation.
- 肺癌侧群细胞microRNA表达谱检测及初步分析
- Feud or Friend? The Role of the miR-17-92 Cluster in Tumorigenesis
- MicroRNA-regulated transgene expression systems for gene therapy and virotherapy.
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- Differential regulation of miR-21 and miR-146a by Epstein–Barr virus-encoded EBNA2
- Cell-Free MicroRNA Expression Profiles in Malignant Effusion Associated with Patient Survival in Non-Small Cell Lung Cancer
- MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells.
- Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer
- MiRNA-26b inhibits proliferation by targeting PTGS2 in breast cancer
- Differential Expression Profiling and Functional Analysis of microRNAs through Stage I-III Papillary Thyroid Carcinoma
- Differential distribution of microRNAs in breast cancer grouped by clinicopathological subtypes.
- Identification of four serum microRNAs from a genome-wide serum microRNA expression profile as potential non-invasive biomarkers for endometrioid endometrial cancer
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