Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis
Explore this paper's citation graph
Summary
It is concluded that miRNA-mediated regulation has a complexity of cellular outcomes and that miRNAs can be mediators of regulation of cell growth and apoptosis pathways.
- Type
- article
- Published
- 2005-03-01
- Cited by
- 1,470
- References
- 30
- Access
- Open access
- OpenAlex
- https://openalex.org/W2098318517
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:1042151
Keywords
microRNA, Biology, Apoptosis, Cell growth, HeLa
References
- Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells.
- The miRNA Registry
- The nuclear RNase III Drosha initiates microRNA processing
- Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs.
- The Drosophila microRNA Mir-14 suppresses cell death and is required for normal fat metabolism.
- MicroRNA-Directed Cleavage of HOXB8 mRNA
- bantam encodes a developmentally regulated microRNA that controls cell proliferation and regulates the proapoptotic gene hid in Drosophila.
- MicroRNAs Modulate Hematopoietic Lineage Differentiation
- Self-assembly of mesoscopically ordered chromatic polydiacetylene/silica nanocomposites
- High expression of precursor microRNA‐155/BIC RNA in children with Burkitt lymphoma
- MicroRNAs and small interfering RNAs can inhibit mRNA expression by similar mechanisms
- Specificity of microRNA target selection in translational repression.
- MicroRNA targets in Drosophila
- The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor.
- Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia
- The microRNA Registry
- The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14.
- Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing.
- MicroRNA maturation: stepwise processing and subcellular localization
- Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans.
Cited by
- The concept of multiple-target anti-miRNA antisense oligonucleotide technology.
- Analyzing micro-RNA expression using microarrays.
- Regulation of cyclin dependent kinase 6 by microRNA 124 in medulloblastoma
- Using cell engineering and omic tools for the improvement of cell culture processes
- P2X7-mediated chemoprevention of epithelial cancers
- Overexpressed miR-494 down-regulates PTEN gene expression in cells transformed by anti-benzo(a)pyrene-trans-7,8-dihydrodiol-9,10-epoxide.
- MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma.
- The Cardiac Transcription Network Modulated by Gata4, Mef2a, Nkx2.5, Srf, Histone Modifications, and MicroRNAs
- MicroRNA‐21 represses human cystathionine gamma‐lyase expression by targeting at specificity protein‐1 in smooth muscle cells
- MiR-21 regulates biological behavior through the PTEN/PI-3 K/Akt signaling pathway in human colorectal cancer cells.
- Differential Expression Profiling and Functional Analysis of microRNAs through Stage I-III Papillary Thyroid Carcinoma
- miR-210: Fine-Tuning the Hypoxic Response
- miR-214: a potential biomarker and therapeutic for different cancers.
- Deregulation between miR-29b/c and DNMT3A Is Associated with Epigenetic Silencing of the CDH1 Gene, Affecting Cell Migration and Invasion in Gastric Cancer
- The potential for liquid biopsies in the precision medical treatment of breast cancer
- MicroRNA与肺癌顺铂耐药相关性研究进展
- Engineering a customized nanodrug delivery system at the cellular level for targeted cancer therapy
- Noncoding miRNAs as key controllers of pancreatic β-cell functions
- The principles of MiRNA-masking antisense oligonucleotides technology.
- The roles of microRNAs in tumorigenesis and angiogenesis.
Related papers
- The Effects of Fluoride on Cell Growth and Protein Synthesis in HeLa Cells
- Effects of iNOS inhibitor 1400 W on the cervical cancer cell line HeLa
- Effect of apoptosis rate on cervical carcinoma cell line HeLa by 4-HPR and Cisplatin
- Research of the apoptosis of TRAIL on cervical cancer HeLa cells
- Inhibition of SAHA on HeLa and p53 Knock-down HeLa-E3 Cells Proliferation
- The Inhibition Effect of the Extract B of Polygonatum Odoratum on Hela Cells
- Serum pharmacological effect of FL on Hela cell
- Effects of combination of sodium glycididazole with cisplatin on sensitivity of cervical carcinoma cell line HeLa
- Inhibiting effect of artemisinin on HeLa cell growth
- The microRNA pathway and cancer