MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias.
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Summary
Genomewide expression profiling of miRNAs in human B cell chronic lymphocytic leukemia (CLL) is reported by using a microarray containing hundreds of human precursor and mature miRNA oligonucleotide probes, suggesting that miRNA expression patterns have relevance to the biological and clinical behavior of this leukemia.
- Type
- article
- Published
- 2004-08-10
- Cited by
- 1,360
- References
- 26
- Access
- Open access
- OpenAlex
- https://openalex.org/W2150696691
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:34322025
Keywords
Chronic lymphocytic leukemia, microRNA, Biology, Gene expression profiling, Computational biology
References
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- Tumor dormancy and metastasis.
- Gene expression regulators —MicroRNAs
- Stem-loop RT-qPCR for microRNA expression profiling.
- Analyzing micro-RNA expression using microarrays.
- miRNAs in cancer: approaches, aetiology, diagnostics and therapy.
- Translational Medicine: microRNAs: a new emerging class of players for disease diagnostics and gene therapy
- Karyotype-specific microRNA signature in chronic lymphocytic leukemia.
- MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia
- MicroRNAs 15a/16-1 function as tumor suppressor genes in multiple myeloma.
- MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursors.
- Overexpressed miR-301a promotes cell proliferation and invasion by targeting RUNX3 in gastric cancer
- miR‐223: infection, inflammation and cancer
- MicroRNAs in prostate cancer
- MicroRNA-506 suppresses tumor proliferation and metastasis in colon cancer by directly targeting the oncogene EZH2
- Dysfunction of microRNA-32 regulates ubiquitin ligase FBXW7 in multiple myeloma disease
- Catalytic hairpin assembly gel assay for multiple and sensitive microRNA detection
- Cancer epigenetics.
- Molecular and Physiological Basis for Hair Loss in Near Naked Hairless and Oak Ridge Rhino-like Mouse Models: Tracking the Role of the Hairless Gene
- Chronic lymphocytic leukemia: molecular genetics and animal models.
- MicroRNA Cancer Regulation
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