The effect of particle design on cellular internalization pathways
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Summary
These findings suggest that HeLa cells readily internalize nonspherical particles with dimensions as large as 3 μm by using several different mechanisms of endocytosis, and it was found that rod-like particles enjoy an appreciable advantage when it comes to internalization rates.
- Type
- article
- Published
- 2008-08-19
- Cited by
- 2,787
- References
- 31
- Access
- Open access
- OpenAlex
- https://openalex.org/W2117630026
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4937171
Keywords
Internalization, Endocytosis, Particle (ecology), Nanotechnology, Particle size
References
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Cited by
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- Investigation of folate-conjugated fluorescent silica nanoparticles for targeting delivery to folate receptor-positive tumors and their internalization mechanism
- Administration, distribution, metabolism and elimination of polymer therapeutics.
- Shape engineering vs organic modification of inorganic nanoparticles as a tool for enhancing cellular internalization
- Quantifying size-dependent interactions between fluorescently labeled polystyrene nanoparticles and mammalian cells
- Top‐Down Fabrication of Polyelectrolyte‐Thermoplastic Hybrid Microparticles for Unidirectional Drug Delivery to Single Cells
- Cationic Antimicrobial Peptides and Biogenic Silver Nanoparticles Kill Mycobacteria without Eliciting DNA Damage and Cytotoxicity in Mouse Macrophages
- How half-coated janus particles enter cells.
- The Aspect Ratio of Nanoparticle Assemblies and the Spatial Arrangement of Ligands can be Optimized to Enhance the Targeting of Cancer Cells
- Molecular shape and immunogenicity of meningococcal polysaccharide group A conjugate vaccine.
- Arginine-rich ionic complementary peptides as potential drug carriers: Impact of peptide sequence on size, shape and cell specificity.
- Synthetic low-density lipoprotein (sLDL) selectively delivers paclitaxel to tumor with low systemic toxicity
- Real-Time Label-Free Monitoring of Nanoparticle Cell Uptake.
- Hydrophobic Effect from Conjugated Chemicals or Drugs on In Vivo Biodistribution of RNA Nanoparticles
- Delivering the right message: Challenges and opportunities in lipid nanoparticles-mediated modified mRNA therapeutics-An innate immune system standpoint.
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- Production and characterisation of carbon-encapsulated iron nanoparticles by arc-discharge plasma
- Implicated Role of Endocytosis in the Internalization and Intracellular Transport of Plasmid DNA During Electric Field-Mediated Gene Delivery
- Toxicological and Immunomodulatory Properties of Mesoporous Silica Particles : Applications in Life Sciences
- Development of PEGylated polyacridine peptides for in vivo gene delivery of plasmid DNA
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