Polylysine-based transfection systems utilizing receptor-mediated delivery.
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Summary
Receptor-mediated gene transfer employs a DNA-binding polycation to compact plasmid DNA to a size that can be taken up by cells to allow internalization by receptor-mediated endocytosis.
- Type
- article
- Published
- 1998-03-02
- Cited by
- 452
- References
- 142
- OpenAlex
- https://openalex.org/W1973174294
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:37528641
Keywords
Polylysine, Internalization, Transfection, Gene delivery, Endocytosis
References
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- Receptor-mediated gene delivery in vivo. Partial correction of genetic analbuminemia in Nagase rats.
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- Membrane damage by hemolytic viruses, toxins, complement, and other cytotoxic agents. A common mechanism blocked by divalent cations.
- Effect of polylysine on the leakage and retention of compounds by Ehrlich ascites tumor cells.
- An array of murine leukemia virus-related elements is transmitted and expressed in a primate recipient of retroviral gene transfer
- Genetic rearrangements occurring during a single cycle of murine leukemia virus vector replication: characterization and implications
- Chicken adenovirus (CELO virus) particles augment receptor-mediated DNA delivery to mammalian cells and yield exceptional levels of stable transformants
- Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs.
- Targeting of genes to the liver with glycoprotein carriers
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- Differential behaviour of lipid based and polycation based gene transfer systems in transfecting primary human fibroblasts: a potential role of polylysine in nuclear transport.
- Terminal glycosylation and disease: Influence on cancer and cystic fibrosis
- Cationic amphipathic histidine-rich peptides for gene delivery.
- The development of gene therapy: from monogenic recessive disorders to complex diseases such as cancer.
- Synthesis of cationic polylactides with tunable charge densities as nanocarriers for effective gene delivery.
- Biscarbamate cross-linked low molecular weight Polyethylenimine polycation as an efficient intra-cellular delivery cargo for cancer therapy
- Cationic methylcellulose derivative with serum-compatibility and endosome buffering ability for gene delivery systems.
- Micelle-like Nanoparticles as Carriers for DNA and siRNA
- The great escape: how cationic polyplexes overcome the endosomal barrier.
- Estudios sobre translocación de complejos DNA-liposomas a través de membranas celulares para mejorar la transfección en células eucariontes (Revisión)
- Association and Dissociation Characteristics of Polymer/DNA Complexes Used for Gene Delivery
- Àcids nucleics químicament modificats amb potencial terapèutic: oligoncleòtids cíclics i àcids nucleics peptídics amb abraçadores de guanina
- Photochemical Transfection: A Technology for Efficient Light-Directed Gene Delivery
- Effect of Dexamethasone Preincubation on Polymer-Mediated Gene Delivery
- Investigating Novel Block Copolypeptide Vesicles for the Enhanced Delivery of Therapeutics
- Design, Synthesis, and Evaluation of New Biodegradable Polymers and Nanoscale Assemblies for Drug Delivery
- Synthesis of diblock copolymer, methoxypoly(ethylene glycol)-block-polyamidoamine dendrimer and its generation-dependent self-assembly with plasmid DNA
- Synthesis of Novel Poly(amido ethylenimine) (PAMEIM) Dendrimer and Its Self-assembly with Plasmid DNA
- Nucleic acid delivery : biocompatible yet efficient platforms
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