Small GTP-binding proteins.
Explore this paper's citation graph
Summary
In this review, functions of small G proteins and their modes of activation and action are described.
- Type
- review
- Published
- 1992-01-01
- Cited by
- 2,600
- References
- 485
- OpenAlex
- https://openalex.org/W2111778006
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:7792305
Keywords
Rab, Ras superfamily, Effector, Cell biology, Biology
References
- Methylation and proteolysis are essential for efficient membrane binding of prenylated p21K‐ras(B).
- A protein geranylgeranyltransferase from bovine brain: implications for protein prenylation specificity.
- Mutants of Saccharomyces cerevisiae defective in the farnesylation of Ras proteins.
- The GTP-binding protein Ran/TC4 is required for protein import into the nucleus
- Identification of ras‐related, YPT family genes in Schizosaccharomyces pombe.
- Molecular cloning of smg p21B and identification of smg p21 purified from bovine brain and human platelets as smg p21B.
- The ral gene: a new ras related gene isolated by the use of a synthetic probe.
- Regulation of the GTPase activity of the ras-like protein p25rab3A. Evidence for a rab3A-specific GAP.
- Post-translational modifications of the C-terminal region of the rho protein are important for its interaction with membranes and the stimulatory and inhibitory GDP/GTP exchange proteins.
- Mechanism of activation of an N‐ras gene in the human fibrosarcoma cell line HT1080.
- ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle.
- rho family GTPase activating proteins p190, bcr and rhoGAP show distinct specificities in vitro and in vivo.
- GDI1 encodes a GDP dissociation inhibitor that plays an essential role in the yeast secretory pathway.
- The mammalian G protein rhoC is ADP‐ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.
- Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade.
- RapV12 antagonizes Ras‐dependent activation of ERK1 and ERK2 by LPA and EGF in Rat‐1 fibroblasts.
- The protein kinase homologue Ste20p is required to link the yeast pheromone response G‐protein beta gamma subunits to downstream signalling components.
- The ras‐related mouse ypt1 protein can functionally replace the YPT1 gene product in yeast.
- Post‐translational processing of p21ras is two‐step and involves carboxyl‐methylation and carboxy‐terminal proteolysis.
- The GTPase Rab3a negatively controls calcium‐dependent exocytosis in neuroendocrine cells.
Cited by
- RAB GTPASE REGULATION OF APICAL CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR RECYCLING IN POLARIZED INTESTINAL EPITHELIAL CELLS
- Phospholipase D, perméabilité endothéliale, et apoptose TNFα dépendante
- Immunolocalization of Rap1 in the Rat Parotid Gland: Detection on Secretory Granule Membranes
- Molecular and Cellular Mechanisms Used in the Acute Phase of Stimulated Steroidogenesis
- Pulmonary endothelial cell signaling and function.
- Mitogen activated protein kinase pathway is involved in RhoC GTPase induced motility, invasion and angiogenesis in inflammatory breast cancer
- Activation of Ras/Erk Pathway by a Novel MET-interacting Protein RanBPM*
- Angiogenic Oligosaccharides of Hyaluronan Induce Multiple Signaling Pathways Affecting Vascular Endothelial Cell Mitogenic and Wound Healing Responses*
- Oncogenic Ras Leads to Rho Activation by Activating the Mitogen-activated Protein Kinase Pathway and Decreasing Rho-GTPase-activating Protein Activity*
- The insulin receptor substrate IRSp53 links postsynaptic shank1 to the small G-protein cdc42.
- Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome
- Novel small GTPase subfamily capable of associating with tubulin is required for chromosome segregation
- RA-RhoGAP, Rap-activated Rho GTPase-activating Protein Implicated in Neurite Outgrowth through Rho*♦
- Cardioprotection from ischemia‐reperfusion injury due to Ras‐GTPase inhibition is attenuated by glibenclamide in the globally ischemic heart
- Mathematical Model for Spatial Segregation of the Rho-Family GTPases Based on Inhibitory Crosstalk
- Synaptic plasticity, AMPA-R trafficking, and Ras-MAPK signaling
- Cloning and characterization of a salt stress-inducible small GTPase gene from the model grass species Lolium temulentum.
- Small GTP-binding proteins and their regulators in cardiac hypertrophy.
- Adenosine–oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton
- Subcellular localization of mRNA and factors involved in translation initiation.