ADP-ribosylation of the rhoA gene product by botulinum C3 exoenzyme causes Swiss 3T3 cells to accumulate in the G1 phase of the cell cycle.
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Summary
The results suggest that the rhoA gene product plays a critical role in G1-S progression in cultured Swiss 3T3 cells and that the ADP-ribosylation abolishes this activity and causes the cells to accumulate in G 1 phase of the cell cycle.
- Type
- article
- Published
- 1993-06-01
- Cited by
- 200
- References
- 0
- OpenAlex
- https://openalex.org/W95359730
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:22278748
Keywords
Exoenzyme, RHOA, Biology, Cell cycle, ADP-ribosylation
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