Drug abuse: hedonic homeostatic dysregulation.
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Summary
This framework provides a realistic approach to identifying the neurobiological factors that produce vulnerability to addiction and to relapse in individuals with a history of addiction.
- Type
- article
- Published
- 1997-10-03
- Cited by
- 2,600
- References
- 70
- OpenAlex
- https://openalex.org/W2090931660
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:24746013
Keywords
Addiction, Psychology, Neuroscience, Reward system, Vulnerability (computing)
References
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- Brain Reward Systems and Abuse
- A theory of intelligent behavior
- Medical Toxicology: Diagnosis and Treatment of Human Poisoning.
- Postcocaine anhedonia. An animal model of cocaine withdrawal.
- Molecular mechanisms of drug addiction [published erratum appears in J Neurosci 1992 Aug;12(8):following table of contents]
- The neurobiology of drug addiction.
- Substance Abuse: A Comprehensive Textbook
- Corticotropin-releasing factor and type 1 corticotropin-releasing factor receptor messenger RNAs in rat brain and pituitary during "binge"-pattern cocaine administration and chronic withdrawal.
- Mesocorticolimbic dopaminergic network: functional and regulatory roles.
- Cannabinoid and heroin activation of mesolimbic dopamine transmission by a common mu1 opioid receptor mechanism.
- Steady-state methadone in rats does not change mRNA levels of corticotropin-releasing factor, its pituitary receptor or proopiomelanocortin.
- GABAA receptor antagonism in the extended amygdala decreases ethanol self-administration in rats.
- A range of research-based pharmacotherapies for addiction.
- Effects of a D1 and a D2 dopamine antagonist on the self-administration of cocaine and piribedil by rhesus monkeys.
- Molecular and cellular basis of addiction.
Cited by
- Pathophysiology of obsessive-compulsive disorder: a necessary link between phenomenology, neuropsychology, imagery and physiology.
- Factors affecting alcohol self-administration : learning, environmental and genetic influences on behaviour
- Compulsive physical activity in adolescents with anorexia nervosa: a psychobehavioral spiral of pathology.
- Satiety threshold: a quantitative model of maintained cocaine self-administration.
- Personality, drug of choice, and comorbid psychopathology among substance abusers.
- Lithium and valproate treatment of pathological gambling: a randomized single-blind study.
- Chronic Hypercortisolemia Inhibits Dopamine Synthesis and Turnover in the Nucleus accumbens: An in vivo Microdialysis Study
- Neurodevelopmental liabilities in alcohol dependence: Central serotonin and dopamine dysfunction
- Wellness programs: legality, fairness, and relevance.
- Effects of Purified Puerarin on Voluntary Alcohol Intake and Alcohol Withdrawal Symptoms in P Rats Receiving Free Access to Water and Alcohol
- Patterns of waterpipe use and dependence: implications for intervention development.
- Sex-related psychological predictors of baseline pain perception and analgesic responses to pentazocine.
- Genetic Determinants of Addiction to Opioids and Cocaine
- The dopamine transporter proteome
- Study of dopamine receptors genes polymorphisms in bipolar patients with comorbid alcohol abuse.
- Decision-Making Dysfunctions in Psychiatry—Altered Homeostatic Processing?
- Involvement of the midbrain tectum in the unconditioned fear promoted by morphine withdrawal.
- Evidence for a role of endogenous neurotensin in the development of sensitization to the locomotor stimulant effect of morphine.
- ADOLESCENT BINGE ALCOHOL EXPOSURE ALTERS HIPPOCAMPAL PROGENITOR CELL PROLIFERATION IN RATS: EFFECTS ON CELL CYCLE KINETICS
- Mixing an Energy Drink with an Alcoholic Beverage Increases Motivation for More Alcohol in College Students
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