Necroptosis: an emerging type of cell death in liver diseases.
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Summary
Understanding the precise mechanism of necroptosis as well as counteracting other cell death pathways in liver diseases could provide a useful insight towards achieving extensive therapeutic significance.
- Type
- review
- Published
- 2014-09-21
- Cited by
- 47
- References
- 55
- Access
- Open access
- OpenAlex
- https://openalex.org/W2087666519
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:207738506
Keywords
Necroptosis, Programmed cell death, Apoptosis, Cell biology, Biology
References
- Fas triggers an alternative, caspase-8–independent cell death pathway using the kinase RIP as effector molecule
- Dichotomy between RIP1- and RIP3-Mediated Necroptosis in Tumor Necrosis Factor-α-Induced Shock
- Necroptosis in Solid Organ Transplantation: A Missing Link to Immune Activation?
- RIPK3‐Mediated Necroptosis Promotes Donor Kidney Inflammatory Injury and Reduces Allograft Survival
- Rip1 (receptor-interacting protein kinase 1) mediates necroptosis and contributes to renal ischemia/reperfusion injury.
- THE DUAL FUNCTIONS OF RIP1 IN FAS-INDUCED HEPATOCYTE DEATH DURING SEPSIS
- Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice
- Necroptosis: an emerging form of programmed cell death.
- TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death
- Classification of cell death
- Phosphorylation-Driven Assembly of RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- Two independent pathways of regulated necrosis mediate ischemia–reperfusion injury
- Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
- The mechanism of necroptosis in normal and cancer cells
- Ferroptosis: an iron-dependent form of nonapoptotic cell death.
- Expansion and evolution of cell death programmes
- New components of the necroptotic pathway
- A Role for Tumor Necrosis Factor Receptor-2 and Receptor-interacting Protein in Programmed Necrosis and Antiviral Responses*
- RIP1, a kinase on the crossroads of a cell's decision to live or die
- Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
Cited by
- MicroRNA-421 participates in vitiligo development through regulating human melanocyte survival by targeting receptor-interacting serine/threonine kinase 1
- Kerr's coining of ‘Apoptosis’ and its relevance in skin wound healing and fibrosis
- Exercise promotes motor functional recovery in rats with corticospinal tract injury: anti-apoptosis mechanism
- The role of necroptosis in neurosurgical diseases
- Different modes of synergistic toxicities between metam/copper (II) and metam/zinc (II) in HepG2 cells: apoptosis vs. necrosis
- Toll pathway modulates TNF-induced JNK-dependent cell death in Drosophila
- Generation of small molecules to interfere with regulated necrosis
- Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis.
- Myc inhibits JNK-mediated cell death in vivo
- Necroptosis: Modules and molecular switches with therapeutic implications.
- Dissection of TLR4-Induced Necroptosis Using Specific Inhibitors of Endocytosis and P38 MAPK
- Sibiriline, a new small chemical inhibitor of receptor‐interacting protein kinase 1, prevents immune‐dependent hepatitis
- Detection of Necroptosis in Ligand-Mediated and Hypoxia-Induced Injury of Hepatocytes Using a Novel Optic Probe-Detecting Receptor-Interacting Protein (RIP)1/RIP3 Binding
- Proteases in Physiology and Pathology
- Does necroptosis have a crucial role in hepatic ischemia-reperfusion injury?
- Inhibition of insulin-like growth factor receptor-1 reduces necroptosis-related markers and attenuates LPS-induced lung injury in mice.
- Serial Monitoring of Immune Markers Being Represented Regulatory T Cell/T Helper 17 Cell Ratio: Indicating Tolerance for Tapering Immunosuppression after Liver Transplantation
- Targeting necroptosis in human disease: potential novel modulators
- RIPK1 Inhibition Enhances Pirarubicin Cytotoxic Efficacy through AKT-P21-dependent Pathway in Hepatocellular Carcinoma
- Methodology of drug screening and target identification for new necroptosis inhibitors
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