Necroptosis: an emerging form of programmed cell death.
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Summary
The signaling pathway, biological effects and pathological significance of this specific form of programmed cell death, characterized as "necroptosis", are summarized.
- Type
- review
- Published
- 2012-06-01
- Cited by
- 268
- References
- 123
- OpenAlex
- https://openalex.org/W1975667190
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:207020195
Keywords
Necroptosis, Programmed cell death, Necrosis, Cell biology, Biology
References
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- Granulysin Induces Cathepsin B Release from Lysosomes of Target Tumor Cells to Attack Mitochondria through Processing of Bid Leading to Necroptosis1
- Combination of Ionising Irradiation and Hyperthermia Activates Programmed Apoptotic and Necrotic Cell Death Pathways in Human Colorectal Carcinoma Cells
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- BNip3 is a mediator of TNF-induced necrotic cell death
- TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival.
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- Classification of cell death
- Phosphorylation-Driven Assembly of RIP1-RIP3 Complex Regulates Programmed Necrosis and Virus-Induced Inflammation
- Necrostatin-1 Reduces Histopathology and Improves Functional Outcome after Controlled Cortical Impact in Mice
Cited by
- Toxic response of graphene nanoplatelets in vivo and in vitro
- Small molecules, big effects: the role of microRNAs in regulation of cardiomyocyte death
- FTY720 induces autophagy-related apoptosis and necroptosis in human glioblastoma cells.
- Necroptosis in tumorigenesis, activation of anti-tumor immunity, and cancer therapy
- Characterization of Iron Response in Gynecological Cell Lines
- Optimizing experimental radioimmunotherapy : investigating the different mechanisms behind radiation induced cell deaths
- Molecular and functional characterization of the signaling pathways that mediate TNF- and TRAIL-induced programmed necrosis.
- [The molecular mechanism of necroptosis].
- RIP1-Dependent Programmed Necrosis is Negatively Regulated by Caspases During Hepatic Ischemia-Reperfusion
- Understanding how injured tissue communicates with the immune system
- INF-γ sensitizes head and neck squamous cell carcinoma cells to chemotherapy-induced apoptosis and necroptosis through up-regulation of Egr-1.
- Contribution of enhanced intrinsic apoptosis to renal ischemia reperfusion injury in the absence of RIPK3 and Caspase-8 dependent regulated cell death
- The role of Sin1 in cell survival
- Oncolytic Viral Therapy Using Reovirus.
- Inhibición de hsp90 como nueva estrategia antitumoral contra el cáncer de páncreas exocrino y el cáncer de colon y recto
- Necroptosis: a potential, promising target and switch in acute pancreatitis
- TAK1 inhibition-induced RIP1-dependent apoptosis in murine macrophages relies on constitutive TNF-α signaling and ROS production
- Caspase-dependent cell death-associated release of nucleosome and damage-associated molecular patterns
- NETs: the missing link between cell death and systemic autoimmune diseases?
- Absence of receptor interacting protein kinase 3 prevents ethanol-induced liver injury
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