A model for receptor-regulated calcium entry.
Explore this paper's citation graph
Summary
A capacitative model is proposed for the mechanism by which activation of surface membrane receptors causes sustained Ca2+ entry into cells from the extracellular space, which allows forCa2+ release and Ca2-mobilization to be controlled by a single messenger, inositol (1,4,5) trisphosphate.
- Type
- review
- Published
- 1986-02-01
- Cited by
- 2,554
- References
- 31
- OpenAlex
- https://openalex.org/W2070832223
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4211981
Keywords
Extracellular, Inositol, Intracellular, Cytosol, Inositol trisphosphate receptor
References
- The possible involvement of phosphatidylinositol breakdown in the mechanism of stimulus-response coupling at receptors which control cell-surface calcium gates.
- Inhibition of phosphatidylinositol synthesis and the inactivation of calcium entry after prolonged exposure of the blowfly salivary gland to 5-hydroxytryptamine.
- Noradrenaline, vasopressin and angiotensin increase Ca2+ influx by opening a common pool of Ca2+ channels in isolated rat liver cells.
- Characteristics of angiotensin II-, K+- and ACTH-induced calcium influx in adrenal glomerulosa cells. Evidence that angiotensin II, K+, and ACTH may open a common calcium channel.
- Phospholipids as ionophores.
- A regulatory calcium-binding site for calcium channel in isolated rat hepatocytes.
- Influence of inositol 1,4,5-trisphosphate and guanine nucleotides on intracellular calcium release within the N1E-115 neuronal cell line.
- Muscarinic, alpha‐adrenergic and peptide receptors regulate the same calcium influx sites in the parotid gland.
- Stepwise enzymatic dephosphorylation of inositol 1,4,5-trisphosphate to inositol in liver
- Proposed mechanism of cholinergic action in smooth muscle
- The second messenger linking receptor activation to internal Ca release in liver
- Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate
- Exchange characteristics of the noradrenaline‐sensitive calcium store in vascular smooth muscle cells or rabbit ear artery.
- Receptor regulation of calcium release and calcium permeability in parotid gland cells.
- Inositol trisphosphate and diacylglycerol as second messengers.
- Failure of phosphatidic acid to translocate Ca2+ across phosphatidylcholine membranes
- Is phosphatidic acid a calcium ionophore under neurohumoral control?
- Nature of the receptor‐regulated calcium pool in the rat parotid gland.
- Inositol trisphosphate, a novel second messenger in cellular signal transduction
- Inositol phospholipids and cell surface receptor function.
Cited by
- Mechanisms of activated Ca2+ entry in the rat pancreatoma cell line, AR4-2J.
- The role of the intracellular signaling pathway in Ehrlichia canis infection in vitro
- Calcium distribution and mobilization in single rat parotid acinar cells investigated by digital imaging microscopy.
- SOC and unSOC.
- Gonadotropin-releasing hormone-induced Ca2+ transients in single identified gonadotropes require both intracellular Ca2+ mobilization and Ca2+ influx.
- Intracellular Ca2+ shift and signal transduction from the tubulovesicular portion of gastric parietal cells during gastrin stimulation or Ca2+ ionophore treatment: comparison between luminescent and fluorescent probes, and electron probe X-ray microanalyzer.
- Repetitive spikes in cytoplasmic calcium evoked by histamine in human endothelial cells
- Inositol(1,3,4,5)tetrakisphosphate-induced activation of sea urchin eggs requires the presence of inositol trisphosphate.
- Depletion of InsP3 stores activates a Ca2+ and K+ current by means of a phosphatase and a diffusible messenger
- Stimulation of ecdysteroidogenesis by small prothoracicotropic hormone: role of calcium.
- Calcium-dependent potentiation of store-operated calcium channels in T lymphocytes
- Store depletion and calcium influx.
- Capacitative Ca2+ entry is involved in cAMP synthesis in mouse parotid acini.
- Slow Feedback Inhibition of Calcium Release-activated Calcium Current by Calcium Entry*
- Rapid Turnover of Calcium in the Endoplasmic Reticulum during Signaling
- Dual effect of tamoxifen, an anti-breast-cancer drug, on intracellular Ca(2+) and cytotoxicity in intact cells.
- Calcium signaling and acute pancreatitis: specific response to a promiscuous messenger.
- Signal transduction in red blood cells of the lizards Ameiva ameiva and Tupinambis merianae (Squamata, Teiidae).
- Mechanisms and physiological significance of the cholinergic control of pancreatic beta-cell function.
- Nitric oxide inhibits capacitative Ca2+ entry by suppression of mitochondrial Ca2+ handling
Related papers
- Metabolism of inositol phosphates in parotid cells: implications for the pathway of the phosphoinositide effect and for the possible messenger role of inositol trisphosphate.
- Inositol 1,2-cyclic 4,5-trisphosphate is an order of magnitude less potent than inositol 1,4,5-trisphosphate in mobilizing intracellular stores of calcium in mouse pancreatic acinar cells.
- Effects of high extracellular calcium concentrations on phosphoinositide turnover and inositol phosphate metabolism in dispersed bovine parathyroid cells
- An essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger production.
- Inositol polyphosphates and intracellular calcium release.
- Actions of inositol phosphates on Ca2+ pools in guinea-pig hepatocytes.
- 707 Targetd disruption of the axonal motor protein KIF1A in the mouse
- The Albert Lasker Medical Awards. Inositol trisphosphate, calcium, lithium, and cell signaling.
- Metabolism of inositol 1,4,5-trisphosphate to higher inositol phosphates in bovine adrenal cytosol.