From endoplasmic-reticulum stress to the inflammatory response
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Summary
New observations suggest that the unfolded-protein response can initiate inflammation, and the coupling of these responses in specialized cells and tissues is now thought to be fundamental in the pathogenesis of inflammatory diseases.
- Type
- review
- Published
- 2008-07-01
- Cited by
- 1,959
- References
- 85
- Access
- Open access
- OpenAlex
- https://openalex.org/W2066538173
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:4351754
Keywords
Endoplasmic reticulum, Unfolded protein response, Cell biology, Inflammation, Protein folding
References
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- PERK-dependent Activation of Nrf2 Contributes to Redox Homeostasis and Cell Survival following Endoplasmic Reticulum Stress*
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- Impairment of the ubiquitin-proteasome system by protein aggregation.
- How Transmembrane Proteins Sense Endoplasmic Reticulum Stress
Cited by
- Estrès del reticle endoplasmàtic, inflamació i resistència a la insulina en cèl•lules musculars esquelètiques
- Role of unfolded protein response in lipogenesis.
- Rôle du stress du réticulum endoplasmique et de l’autophagie dans la régulation des réponses immune et angiogénique activées par des stress ischémiques et inflammatoires dans l’épithélium rénal humain
- Classical swine fever virus NS2 protein promotes interleukin-8 expression and inhibits MG132-induced apoptosis
- Eukaryotic initiation factor 2α phosphorylation is required for B-cell maturation and function in mice
- On PAR with PARP: cellular stress signaling through poly(ADP-ribose) and PARP-1.
- L’oxydation modifie les effets métaboliques d'acides gras polyinsaturés de la série n-3 incorporés par différents vecteurs dans des régimes hyperlipidiques : contribution de l’absorption intestinale et de la réactivité cellulaire du 4-hydroxy-hexénal
- IRE1α -XBP1s Induces PDI Expression to Increase MTP Activity for Hepatic VLDL Assembly and Lipid Homeostasis
- Progesterone regulates the expression and activity of two mouse isoforms of the glycoprotein folding sensor UDP-Glc: glycoprotein glucosyltransferase (UGGT).
- Endoplasmic reticulum stress mediates house dust mite-induced airway epithelial apoptosis and fibrosis
- Expression of markers of endoplasmic reticulum stress-induced apoptosis in the placenta of women with early and late onset severe pre-eclampsia.
- Mycobacterium tuberculosis PPE32 promotes cytokines production and host cell apoptosis through caspase cascade accompanying with enhanced ER stress response
- Detrimental effects of nicotine on thioacetamide-induced liver injury in mice
- Nutrient excess and autophagic deficiency: explaining metabolic diseases in obesity.
- Structural insight into the protective role of P58(IPK) during unfolded protein response.
- Selenoprotein S inhibits inflammation-induced vascular smooth muscle cell calcification
- Melatonin inhibits endoplasmic reticulum stress‐associated TXNIP/NLRP3 inflammasome activation in lipopolysaccharide‐induced endometritis in mice
- Proteomics Study of Peripheral Blood Mononuclear Cells (PBMCs) in Autistic Children
- Pyroptosis is a critical inflammatory pathway in the placenta from early onset preeclampsia and in human trophoblasts exposed to hypoxia and endoplasmic reticulum stressors
- Neuroinflammation in Overnutrition-induced Diseases
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