From endoplasmic-reticulum stress to the inflammatory response

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Summary

New observations suggest that the unfolded-protein response can initiate inflammation, and the coupling of these responses in specialized cells and tissues is now thought to be fundamental in the pathogenesis of inflammatory diseases.

Type
review
Published
2008-07-01
Cited by
1,959
References
85
Access
Open access

Keywords

Endoplasmic reticulum, Unfolded protein response, Cell biology, Inflammation, Protein folding

References

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