Eukaryotic initiation factor 2α phosphorylation is required for B-cell maturation and function in mice
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Summary
The data suggest that regulation of translation through eIF2α phosphorylation is dispensable in hematopoietic reconstitution but essential during late B-cell development.
- Type
- article
- Published
- 2011-09-01
- Cited by
- 5
- References
- 20
- Access
- Open access
- OpenAlex
- https://openalex.org/W21565905
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:6895416
Keywords
Humanities, Art
References
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- Phosphorylation of initiation factor‐2α is required for activation of internal translation initiation during cell differentiation
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- The follicular versus marginal zone B lymphocyte cell fate decision
- Rapid B Cell Receptor-induced Unfolded Protein Response in Nonsecretory B Cells Correlates with Pro- Versus Antiapoptotic Cell Fate*
- Internal Ribosome Entry Site-mediated Translation of a Mammalian mRNA Is Regulated by Amino Acid Availability*
- IκBα is required for marginal zone B cell lineage development
- Regulation of Internal Ribosome Entry Site-mediated Translation by Eukaryotic Initiation Factor-2α Phosphorylation and Translation of a Small Upstream Open Reading Frame*
- Molecular mechanisms of translational control
- Activation of the integrated stress response during T helper cell differentiation
- From endoplasmic-reticulum stress to the inflammatory response
- Aberrant Eukaryotic Translation Initiation Factor 4E-Dependent mRNA Transport Impedes Hematopoietic Differentiation and Contributes to Leukemogenesis
- Activated Notch1 signaling promotes tumor cell proliferation and survival in Hodgkin and anaplastic large cell lymphoma.
- Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
- Translational control is required for the unfolded protein response and in vivo glucose homeostasis.
- The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver
- Halofuginone Inhibits TH17 Cell Differentiation by Activating the Amino Acid Starvation Response
- Translational control of C/EBPalpha and C/EBPbeta isoform expression.
- The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.
- [Initiation of protein synthesis in eukaryotic cells].
Cited by
- Metabolic Links between Plasma Cell Survival, Secretion, and Stress
- Metabolic and Transcriptional Modules Independently Diversify Plasma Cell Lifespan and Function
- Antibody repertoire and gene expression dynamics of diverse human B cell states during affinity maturation
- B-1b Cells Have Unique Functional Traits Compared to B-1a Cells at Homeostasis and in Aged Hyperlipidemic Mice With Atherosclerosis
- Integrated Stress Response (ISR) Pathway: Unraveling Its Role in Cellular Senescence
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