Protein structure prediction on the Web: a case study using the Phyre server
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Summary
This protocol provides a guide to interpreting the output of structure prediction servers in general and one such tool in particular, the protein homology/analogy recognition engine (Phyre), which can reliably detect up to twice as many remote homologies as standard sequence-profile searching.
- Type
- article
- Published
- 2009-02-26
- Cited by
- 4,561
- References
- 29
- OpenAlex
- https://openalex.org/W2060259273
- Semantic Scholar
- https://api.semanticscholar.org/CorpusID:12497300
Keywords
Protein structure prediction, Computer science, Web server, Protein structure database, Protein structure
References
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- Savicalin, a lipocalin from hemocytes of the soft tick, Ornithodoros savignyi
- ePlant and the 3D Data Display Initiative: Integrative Systems Biology on the World Wide Web
- HMMerThread: Detecting Remote, Functional Conserved Domains in Entire Genomes by Combining Relaxed Sequence-Database Searches with Fold Recognition
- A discovery 70 years in the making: characterization of the Rose rosette virus.
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- Aicardi-Goutières Syndrome Gene and HIV-1 Restriction Factor SAMHD1 Is a dGTP-regulated Deoxynucleotide Triphosphohydrolase*♦
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- Investigating the Allosteric Regulation of YfiN from Pseudomonas aeruginosa: Clues from the Structure of the Catalytic Domain
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